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1. WO2022006231 - DPAGT1 INHIBITORS OF CAPURAMYCIN ANALOGUES AND THEIR ANTIMIGRATORY ACTIVITIES OF SOLID TUMORS

Publication Number WO/2022/006231
Publication Date 06.01.2022
International Application No. PCT/US2021/039826
International Filing Date 30.06.2021
IPC
C07H 19/06 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof
02sharing nitrogen
04Heterocyclic radicals containing only nitrogen as ring hetero atom
06Pyrimidine radicals
Applicants
  • UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION [US]/[US]
  • CALIFORNIA INSTITUTE OF TECHNOLOGY [US]/[US]
Inventors
  • KUROSU, Michio
  • MITACHI, Katsuhiko
  • CLEMONS, William, M.
Agents
  • TRINQUE, Brian, C.
  • KERNER, Shann
  • BARTON, Steven, K.
  • CHEN, Xiaoyue (peter)
  • DECONTI, Giulio, A.
Priority Data
63/046,10330.06.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) DPAGT1 INHIBITORS OF CAPURAMYCIN ANALOGUES AND THEIR ANTIMIGRATORY ACTIVITIES OF SOLID TUMORS
(FR) INHIBITEURS DE DPAGT1 D'ANALOGUES DE CAPURAMYCINE ET LEURS ACTIVITÉS ANTIMIGRATOIRES DE TUMEURS SOLIDES
Abstract
(EN) Provided herein are compounds and methods of using these compounds to treat disorders related to DPAGT1 function, including cancer and bacterial infections.
(FR) L'invention concerne des composés et des procédés d'utilisation de ces composés pour traiter des troubles liés à la fonction de DPAGT1, y compris le cancer et les infections bactériennes.
Latest bibliographic data on file with the International Bureau