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1. WO2022006071 - COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY

Publication Number WO/2022/006071
Publication Date 06.01.2022
International Application No. PCT/US2021/039557
International Filing Date 29.06.2021
IPC
C07K 14/705 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
C07K 14/36 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195from bacteria
36from Actinomyces; from Streptomyces (G)
Applicants
  • THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US]/[US]
Inventors
  • ISACOFF, Ehud Y.
  • DONTHAMSETTI, Prashant Chandra
Agents
  • BORDEN, Paula A.
Priority Data
63/046,32930.06.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY
(FR) COMPOSITIONS ET PROCÉDÉS PERMETTANT DE MODULER L'ACTIVITÉ DU RÉCEPTEUR DE LA DOPAMINE
Abstract
(EN) The present disclosure provides conjugates and systems for modulating the activity of a ligand-binding polypeptide such as a D1 dopamine receptor. The present disclosure provides methods of modulating the activity of a D1 dopamine receptor. The present disclosure provides methods of treating Parkinson's disease in an individual.
(FR) La présente divulgation concerne des conjugués et des systèmes permettant de moduler l'activité d'un polypeptide se liant aux ligands, tel qu'un récepteur D1 de la dopamine. La présente divulgation concerne des procédés de modulation de l'activité du récepteur D1 de la dopamine. La présente divulgation concerne des méthodes de traitement de la maladie de Parkinson chez un individu.
Latest bibliographic data on file with the International Bureau