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1. WO2022005590 - A METHOD FOR THE DEGRADATION OF ENDOGENOUS PROTEIN

Publication Number WO/2022/005590
Publication Date 06.01.2022
International Application No. PCT/US2021/029795
International Filing Date 29.04.2021
IPC
A61K 47/62 2017.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
62the modifying agent being a protein, peptide or polyamino acid
A61K 47/69 2017.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
69the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
A61P 35/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61K 39/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
Applicants
  • UNIVERSITY OF SOUTH CAROLINA [US]/[US]
Inventors
  • XU, Peisheng
Agents
  • LINEBERRY, Douglas L.
  • THORSON, Chad L.
  • JOHNSON, III, John E.
  • QUIRK, Nathaniel T.
Priority Data
17/242,64728.04.2021US
63/045,27529.06.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) A METHOD FOR THE DEGRADATION OF ENDOGENOUS PROTEIN
(FR) MÉTHODE DE DÉGRADATION DE PROTÉINE ENDOGÈNE
Abstract
(EN) Described herein are systems and methods for the degradation of endogenous protein with the help of a nanocarrier, which has the advantage of easy scale-up and feasibility for in vivo application.
(FR) L'invention concerne des systèmes et des méthodes pour la dégradation de protéine endogène à l'aide d'un nanovecteur, ce qui présente l'avantage d'une mise à l'échelle et d'une faisabilité faciles pour une application in vivo.
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