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1. WO2022005203 - PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF NEPHROTOXICITY AND KIDNEY FIBROTIC DISEASE COMPRISING DENDROPANAX MORBIFERA LEVEILLE EXTRACT OR COMPOUND DERIVED THEREFROM

Publication Number WO/2022/005203
Publication Date 06.01.2022
International Application No. PCT/KR2021/008266
International Filing Date 30.06.2021
IPC
A61K 36/25 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
A61K 31/343 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
34having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
343condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
A61P 13/12 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13Drugs for disorders of the urinary system
12of the kidneys
A61P 43/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
A23L 33/105 2016.1
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
105Plant extracts, their artificial duplicates or their derivatives
Applicants
  • 주식회사 고암바이오알앤디수 KABIO R&D SOO CO., LTD. [KR]/[KR]
  • 성균관대학교산학협력단 RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY [KR]/[KR]
Inventors
  • 곽종환 KWAK, Jong-Hwan
  • 김형식 KIM, Hyung-Sik
  • 박재현 PARK, Jae-Hyeon
Agents
  • 위병갑 WIE, Byoung-Gap
Priority Data
10-2020-008018130.06.2020KR
Publication Language Korean (ko)
Filing Language Korean (KO)
Designated States
Title
(EN) PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF NEPHROTOXICITY AND KIDNEY FIBROTIC DISEASE COMPRISING DENDROPANAX MORBIFERA LEVEILLE EXTRACT OR COMPOUND DERIVED THEREFROM
(FR) COMPOSITION PHARMACEUTIQUE DESTINÉE À LA PRÉVENTION ET AU TRAITEMENT DE LA NÉPHROTOXICITÉ ET D'UNE MALADIE FIBROTIQUE RÉNALE COMPRENANT UN EXTRAIT DE DENDROPANAX MORBIFERA LEVEILLE OU UN COMPOSÉ DÉRIVÉ DE CE DERNIER
(KO) 황칠나무 추출물 또는 이로부터 유래된 화합물을 포함하는 신장독성 및 신장섬유화 질환의 예방 및 치료용 약학적 조성물
Abstract
(EN) The present invention relates to a use of Dendropanax morbifera Leveille extract or dendropanoxide isolated therefrom in the alleviation of nephrotoxicity and the treatment of kidney fibrotic disease. The Dendropanax morbifera Leveille extract or dendropanoxide isolated therefrom of the present invention reduces oxidative stress and reduces inflammatory cytokines and thus can be advantageously used for the prevention and treatment of nephrotoxicity and kidney fibrotic disease.
(FR) La présente invention se rapporte à une utilisation d'extrait de Dendropanax morbifera Leveille ou de dendropanoxyde isolé à partir de ce dernier dans le soulagement de la néphrotoxicité et le traitement d'une maladie fibrotique rénale. L'extrait de Dendropanax morbifera Leveille ou le dendropanoxyde isolé à partir de ce dernier de la présente invention réduit le stress oxydatif et réduit les cytokines inflammatoires et peut donc être avantageusement utilisé pour la prévention et le traitement de la néphrotoxicité et de maladies fibrotiques rénales.
(KO) 본 발명은 황칠나무 추출물 또는 이로부터 분리된 덴드로파녹시드(dendropanoxide)의 신장독성 완화 및 신장 섬유화 질환의 치료 용도에 관한 것으로, 본 발명의 황칠나무 추출물 또는 이로부터 분리된 덴드로파녹시드는 산화 스트레스를 감소시키고 염증성 사이토카인을 감소시켜 신장독성 및 신장 섬유화 질환의 예방 및 치료에 유용하게 이용될 수 있다.
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