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1. WO2022005106 - METHOD FOR PREPARING COMPOSITION FOR CULTURING PANCREATIC ORGANOIDS, COMPOSITION THEREFOR, AND METHOD FOR CULTURING ORGANOIDS BY USING SAME

Publication Number WO/2022/005106
Publication Date 06.01.2022
International Application No. PCT/KR2021/007963
International Filing Date 24.06.2021
IPC
C12N 5/00 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
C12N 5/071 2010.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07Animal cells or tissues
071Vertebrate cells or tissues, e.g. human cells or tissues
Applicants
  • 주식회사 인터파크바이오컨버전스 INTERPARK BIO CONVERGENCE CORP. [KR]/[KR]
  • 포항공과대학교 산학협력단 POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION [KR]/[KR]
Inventors
  • 이하람 LEE, Ha Ram
  • 장진아 JANG, Jin Ah
  • 최유미 CHOI, Yoo Mi
  • 황동규 HWANG, Dong Gyu
  • 김명지 KIM, Myung Ji
Agents
  • 김영호 KIM, Young Ho
Priority Data
10-2020-008051430.06.2020KR
10-2021-005694330.04.2021KR
Publication Language Korean (ko)
Filing Language Korean (KO)
Designated States
Title
(EN) METHOD FOR PREPARING COMPOSITION FOR CULTURING PANCREATIC ORGANOIDS, COMPOSITION THEREFOR, AND METHOD FOR CULTURING ORGANOIDS BY USING SAME
(FR) PROCÉDÉ DE PRÉPARATION D'UNE COMPOSITION POUR LA CULTURE D'ORGANOÏDES PANCRÉATIQUES, COMPOSITION À CET EFFET, ET PROCÉDÉ DE CULTURE D'ORGANOÏDES L'UTILISANT
(KO) 췌장 오가노이드 배양용 조성물의 제조 방법, 그 조성물 및 이를 이용한 오가노이드 배양 방법
Abstract
(EN) The present invention relates to a method for preparing a composition for culturing pancreatic organoids, a composition therefor, and a method for culturing organoids by using same. The present invention can form an environment that is more similar than that of a conventional matrigel-based culture system to real tissue and, particularly, achieves, in pancreatic organoid culturing, the effects of promoting tissue differentiation and effectively developing same into a form similar to that of real tissue.
(FR) La présente invention concerne un procédé de préparation d'une composition pour la culture d'organoïdes pancréatiques, une composition pour celle-ci, et un procédé de culture d'organoïdes l'utilisant. La présente invention peut former un environnement plus proche d'un tissu réel que celui d'un système de culture conventionnel à base de matrigel et, en particulier, permet d'obtenir, dans la culture d'organoïdes pancréatiques, les effets de la promotion de la différenciation des tissus et de leur développement efficace sous une forme similaire à celle d'un tissu réel.
(KO) 본 발명은 췌장 오가노이드 배양용 조성물의 제조 방법, 그 조성물 및 이를 이용한 오가노이드 배양 방법에 관한 것으로, 본 발명은 기존의 매트리겔 기반 배양 시스템 대비하여 실제 조직 유사 환경을 조성할 수 있고, 특히 췌장 오가노이드 배양에 있어서 조직 분화를 촉진시키고 실제 조직과 유사한 형태로 효과적으로 발달시키는 효과를 발휘한다.
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