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1. WO2022004864 - HUMAN LONG-TERM HEMATOPOIETIC STEM CELL MARKER

Publication Number WO/2022/004864
Publication Date 06.01.2022
International Application No. PCT/JP2021/025050
International Filing Date 01.07.2021
IPC
C12N 5/071 2010.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07Animal cells or tissues
071Vertebrate cells or tissues, e.g. human cells or tissues
A61K 35/28 2015.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
A61P 3/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
A61P 3/06 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
06Antihyperlipidemics
A61P 7/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
7Drugs for disorders of the blood or the extracellular fluid
A61P 31/18 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
18for HIV
Applicants
  • ネクスジェン株式会社 NEXTGEM INC. [JP]/[JP]
Inventors
  • 宮西 正憲 MIYANISHI Masanori
  • 宮塚 功 MIYATSUKA Isao
  • リー マイ アン Le My An
Agents
  • 小野 誠 ONO Makoto
  • 川嵜 洋祐 KAWASAKI Yosuke
  • 市川 祐輔 ICHIKAWA Yusuke
Priority Data
2021-08950227.05.2021JP
PCT/JP2020/02591501.07.2020JP
Publication Language Japanese (ja)
Filing Language Japanese (JA)
Designated States
Title
(EN) HUMAN LONG-TERM HEMATOPOIETIC STEM CELL MARKER
(FR) MARQUEUR DE CELLULES SOUCHES HÉMATOPOÏÉTIQUES À LONG TERME HUMAIN
(JA) ヒト長期造血幹細胞マーカー
Abstract
(EN) The present disclosure relates to: a marker for concentrating or isolating hematopoietic stem cells and a method for using the same; cells or a cell aggregate isolated or concentrated by the marker; a method for using the cells or cell aggregate; a drug containing the cells or cell aggregate; and a classifier obtained using the cells or cell aggregate.
(FR) La présente invention concerne : un marqueur pour concentrer ou isoler des cellules souches hématopoïétiques et un procédé d'utilisation de celui-ci ; des cellules ou un agrégat cellulaire isolé ou concentré par le marqueur ; un procédé d'utilisation des cellules ou de l'agrégat cellulaire ; un médicament contenant les cellules ou l'agrégat cellulaire ; et un classificateur obtenu à l'aide des cellules ou de l'agrégat cellulaire.
(JA) 本開示は、造血幹細胞を濃縮または単離するためのマーカー並びにこれを利用する方法、前記マーカーによって単離または濃縮された細胞または細胞集団、前記細胞または細胞集団を利用する方法、前記細胞または細胞集団を含有する医薬、前記細胞または細胞集団を利用して得られる分類器に関する。
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