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1. WO2022004788 - AMELIORATING AGENT OR PROPHYLACTIC AGENT FOR MUSCLE WEAKNESS SYMPTOM IN DISEASE OR SYNDROME ASSOCIATED WITH METABOLIC DISORDER

Publication Number WO/2022/004788
Publication Date 06.01.2022
International Application No. PCT/JP2021/024759
International Filing Date 30.06.2021
IPC
A61K 31/485 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
485Morphinan derivatives, e.g. morphine, codeine
A61P 3/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
A61P 21/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
21Drugs for disorders of the muscular or neuromuscular system
Applicants
  • 東レ株式会社 TORAY INDUSTRIES, INC. [JP]/[JP]
Inventors
  • 大森 優 OMORI Yu
  • 内田 将史 UCHIDA Masashi
Agents
  • 特許業務法人平木国際特許事務所 HIRAKI & ASSOCIATES
Priority Data
2020-11248630.06.2020JP
2021-09768411.06.2021JP
Publication Language Japanese (ja)
Filing Language Japanese (JA)
Designated States
Title
(EN) AMELIORATING AGENT OR PROPHYLACTIC AGENT FOR MUSCLE WEAKNESS SYMPTOM IN DISEASE OR SYNDROME ASSOCIATED WITH METABOLIC DISORDER
(FR) AGENT D'AMÉLIORATION OU AGENT PROPHYLACTIQUE POUR SYMPTÔME DE FAIBLESSE MUSCULAIRE DANS UNE MALADIE OU UN SYNDROME ASSOCIÉ À UN TROUBLE MÉTABOLIQUE
(JA) 代謝異常を伴う疾患又は症候群における筋力低下症状の改善剤又は予防剤
Abstract
(EN) The present invention addresses the problem of providing an ameliorating agent or a prophylactic agent for a muscle weakness symptom in a disease or a syndrome associated with a metabolic disorder. The present invention provides an ameliorating agent or a prophylactic agent for a muscle weakness symptom in a disease or a syndrome associated with a metabolic disorder, the agent containing a compound having a morphinan backbone structure typified by the below-mentioned compound or a pharmacologically acceptable acid addition salt thereof as an active ingredient.
(FR) La présente invention aborde le problème de la fourniture d'un agent d'amélioration ou d'un agent prophylactique pour un symptôme de faiblesse musculaire dans une maladie ou un syndrome associé à un trouble métabolique. La présente invention concerne un agent d'amélioration ou un agent prophylactique pour un symptôme de faiblesse musculaire dans une maladie ou un syndrome associé à un trouble métabolique, l'agent contenant un composé ayant une structure de squelette de morphinane caractérisée par le composé mentionné ci-dessous ou un sel d'addition d'acide pharmacologiquement acceptable de celui-ci en tant que principe actif.
(JA) 代謝異常を伴う疾患又は症候群における筋力低下症状の改善剤又は予防剤を提供することを課題とする。本発明は、下記化合物に代表されるモルヒナン骨格を有する化合物又はその薬理学的に許容される酸付加塩を有効成分として含有する、代謝異常を伴う疾患又は症候群における筋力低下症状の改善剤又は予防剤を提供する。
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