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1. WO2022004783 - METHOD FOR PRODUCING MORPHINAN DERIVATIVE

Publication Number WO/2022/004783
Publication Date 06.01.2022
International Application No. PCT/JP2021/024733
International Filing Date 30.06.2021
IPC
C07D 489/02 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
489Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro furan ring systems, e.g. derivatives of -morphinan of the formula:
02with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
A61K 31/485 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
485Morphinan derivatives, e.g. morphine, codeine
A61P 25/04 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
04Centrally acting analgesics, e.g. opioids
A61P 25/36 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
30for treating abuse or dependence
36Opioid-abuse
A61P 43/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
C07B 61/00 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
61Other general methods
Applicants
  • 日本ケミファ株式会社 NIPPON CHEMIPHAR CO., LTD. [JP]/[JP]
Inventors
  • 廣瀬 雅朗 HIROSE Masaaki
Agents
  • 砂原 一公 SUNAHARA Hisato
  • 千草 新一 CHIGUSA Shinichi
  • 清 一雄 SEI Kazuo
Priority Data
2020-11231030.06.2020JP
Publication Language Japanese (ja)
Filing Language Japanese (JA)
Designated States
Title
(EN) METHOD FOR PRODUCING MORPHINAN DERIVATIVE
(FR) PROCÉDÉ DE PRODUCTION D'UN DÉRIVÉ DE MORPHINANE
(JA) モルヒナン誘導体の製造方法
Abstract
(EN) This method for producing a morphinan derivative by means of a reduction reaction using formic acid or the like is represented by the following general formula (II).
(FR) L'invention concerne un procédé de production d'un dérivé de morphinane au moyen d'une réaction de réduction à l'aide d'acide formique ou analogue, représenté par la formule générale suivante (II).
(JA) ギ酸等を用いた還元反応による次の一般式(II)で表されるモルヒナン誘導体の製造方法。
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