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1. WO2022004054 - STAT3 PHOSPHORYLATION INHIBITOR, AND PROPHYLACTIC OR THERAPEUTIC AGENT FOR AUTOIMMUNE DISEASE AND CORONAVIRUS INFECTION

Publication Number WO/2022/004054
Publication Date 06.01.2022
International Application No. PCT/JP2021/007780
International Filing Date 01.03.2021
IPC
A61K 38/22 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
22Hormones
A61P 31/14 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
A61P 31/16 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
16for influenza or rhinoviruses
A61P 37/06 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
02Immunomodulators
06Immunosuppressants, e.g. drugs for graft rejection
A61P 43/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
Applicants
  • 国立大学法人東北大学 TOHOKU UNIVERSITY [JP]/[JP]
Inventors
  • 大河内 眞也 OHKOUCHI, Shinya
  • 兼平 雅彦 KANEHIRA, Masahiko
  • 岡田 克典 OKADA, Yoshinori
  • 黒澤 一 KUROSAWA, Hajime
Agents
  • 特許業務法人三枝国際特許事務所 SAEGUSA & PARTNERS
Priority Data
2020-11268030.06.2020JP
Publication Language Japanese (ja)
Filing Language Japanese (JA)
Designated States
Title
(EN) STAT3 PHOSPHORYLATION INHIBITOR, AND PROPHYLACTIC OR THERAPEUTIC AGENT FOR AUTOIMMUNE DISEASE AND CORONAVIRUS INFECTION
(FR) INHIBITEUR DE PHOSPHORYLATION DE STAT3 ET AGENT PROPHYLACTIQUE OU THÉRAPEUTIQUE CONTRE UNE MALADIE AUTO-IMMUNE ET UNE INFECTION À CORONAVIRUS
(JA) STAT3のリン酸化抑制剤、自己免疫疾患及びコロナウイルス感染症の予防又は治療剤
Abstract
(EN) An inhibitor of the phosphorylation of STAT3, which contains stanniocalcin-1 (STC1) as an active ingredient. An inhibitor of the expression or phosphorylation of JAK, which contains stanniocalcin-1 as an active ingredient. A prophylactic or therapeutic agent for an autoimmune disease, which contains stanniocalcin-1 as an active ingredient. A prophylactic or therapeutic agent for an influenza virus infection, which contains stanniocalcin-1 as an active ingredient. A prophylactic or therapeutic agent for a coronavirus infection, which contains stanniocalcin-1 as an active ingredient.
(FR) La présente invention concerne un inhibiteur de la phosphorylation de STAT3, qui contient de la stanniocalcine-1 (STC1) utilisée comme principe actif. La présente invention concerne également un inhibiteur de l'expression ou de la phosphorylation de JAK, qui contient de la stanniocalcine-1 utilisée comme principe actif. L'invention concerne en outre un agent prophylactique ou thérapeutique contre une maladie auto-immune, qui contient de la stanniocalcine-1 utilisée comme principe actif. L'invention concerne également un agent prophylactique ou thérapeutique contre une infection par un virus de la grippe, qui contient de la stanniocalcine-1 utilisée comme principe actif. L'invention concerne en outre un agent prophylactique ou thérapeutique contre une infection à coronavirus, qui contient de la stanniocalcine-1 utilisée comme principe actif.
(JA) スタニオカルシン1(STC1)を有効成分として含有する、STAT3のリン酸化抑制剤。スタニオカルシン1を有効成分として含有する、JAKの発現又はリン酸化抑制剤。スタニオカルシン1を有効成分として含有する、自己免疫疾患の予防又は治療剤。スタニオカルシン1を有効成分として含有する、インフルエンザウイルス感染症の予防又は治療剤。スタニオカルシン1を有効成分として含有する、コロナウイルス感染症の予防又は治療剤。
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