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1. WO2022003643 - STABLE SOLID FORMULATION OF AZILSARTAN KAMEDOXOMIL, OR AZILSARTAN OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF

Publication Number WO/2022/003643
Publication Date 06.01.2022
International Application No. PCT/IB2021/055957
International Filing Date 02.07.2021
IPC
A61K 31/4245 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
4245Oxadiazoles
A61K 9/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
A61K 9/20 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, lozenges or tablets
A61P 9/12 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
12Antihypertensives
A61K 31/4035 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403condensed with carbocyclic rings, e.g. carbazole
4035Isoindoles, e.g. phthalimide
Applicants
  • PIRAMAL PHARMA LIMITED [IN]/[IN]
Inventors
  • BARABDE, Umesh
  • KHARAT, Vishakh
  • JAIN, Amit
  • SINGARE, Dhananjay
  • NAIK, Mahek
  • SHARMA, Nawanit
Priority Data
20202102844403.07.2020IN
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) STABLE SOLID FORMULATION OF AZILSARTAN KAMEDOXOMIL, OR AZILSARTAN OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF
(FR) FORMULATION SOLIDE STABLE D'AZILSARTAN KAMÉDOXOMIL, OU D'AZILSARTAN OU DE SES SELS PHARMACEUTIQUEMENT ACCEPTABLES
Abstract
(EN) The present invention relates to a stable, solid pharmaceutical composition of Azilsartan or its pharmaceutically acceptable salts thereof and one or more pharmaceutically acceptable excipient(s) and processes for its preparation; optionally, the said composition further comprises a diuretic, preferably a thiazide diuretic such as Chlorthalidone. The present invention further relates to a stable, solid pharmaceutical composition comprising Azilsartan kamedoxomil and one or more pharmaceutically acceptable excipient(s).
(FR) La présente invention concerne une composition pharmaceutique solide stable d'azilsartan ou de ses sels pharmaceutiquement acceptables et un ou plusieurs excipient(s) pharmaceutiquement acceptable(s) et ses procédés de préparation ; facultativement, ladite composition comprend en outre un diurétique, de préférence un diurétique thiazidique tel que la chlortalidone. La présente invention concerne en outre une composition pharmaceutique solide stable comprenant de l'azilsartan kamédoxomil et un ou plusieurs excipient(s) pharmaceutiquement acceptable(s).
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