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1. WO2022003584 - PREPARATION OF A PYRIMIDINYL-3,8-DIAZABICYCLO[3.2.1]OCTANYLMETHANONE DERIVATIVE AND SALT THEREOF

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Publication Number WO/2022/003584
Publication Date 06.01.2022
International Application No. PCT/IB2021/055854
International Filing Date 30.06.2021
IPC
C07D 487/08 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02in which the condensed system contains two hetero rings
08Bridged systems
CPC
C07D 487/08
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
02in which the condensed system contains two hetero rings
08Bridged systems
Applicants
  • PFIZER INC. [US]/[US]
Inventors
  • GOETZ, Adam Edward
  • RUGGERI, Sally Gut
  • SINGER, Robert Alan
Agents
  • RUGGIERO, Charles N. J.
Priority Data
63/047,59002.07.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) PREPARATION OF A PYRIMIDINYL-3,8-DIAZABICYCLO[3.2.1]OCTANYLMETHANONE DERIVATIVE AND SALT THEREOF
(FR) PRÉPARATION D'UN DÉRIVÉ DE PYRIMIDINYL-3,8-DIAZABICYCLO[3.2.1]OCTANYLMÉTHANONE ET SEL DE CELUI-CI
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Abstract
(EN) Methods for preparing ((S)-2,2-difluorocyclopropyl)-((1R,5S)-3-(2-((1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]-octan-8-yl)methanone and intermediates used in the processes of preparation thereof.
(FR) L'invention concerne des procédés de préparation de la ((S)-2,2-difluorocyclopropyl)-((1R,5S)-3-(2-((1-méthyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]-octan-8-yl)méthanone et des intermédiaires utilisés dans les processus de préparation associés.
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