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1. WO2022003572 - METHOD FOR DETECTING COLORECTAL CANCER

Publication Number WO/2022/003572
Publication Date 06.01.2022
International Application No. PCT/IB2021/055828
International Filing Date 29.06.2021
IPC
C12Q 1/6886 2018.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
6886for cancer
Applicants
  • EPIFY B.V. [NL]/[NL]
  • UNIVERSITEIT MAASTRICHT
  • ACADEMISCH ZIEKENHUIS MAASTRICHT [NL]/[NL]
Inventors
  • KOCH, Alexander
  • VAN NESE, Leander
  • VAN ENGELAND, Manon
Agents
  • SPENCER, Matthew Peter
Priority Data
63/045,46829.06.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) METHOD FOR DETECTING COLORECTAL CANCER
(FR) MÉTHODE DE DÉTECTION DU CANCER COLORECTAL
Abstract
(EN) The disclosed subject matter is in the field of molecular diagnostics, and in particular provides diagnostic markers, methods, systems, and kits for detecting a predisposition to, or the presence of colorectal cancer (CRC), such as detecting a change in the expression status or methylation status, or a combination thereof of any one or more of a number of genes. Also described are pharmacogenetic methods for determining suitable treatment regimens for cancer and methods for treating cancer patients, based around selection of the patients according to the disclosed methods.
(FR) L'objet divulgué se rapporte au domaine du diagnostic moléculaire et concerne en particulier des marqueurs de diagnostic, des procédés, des systèmes et des kits pour détecter une prédisposition à, ou la présence d'un cancer colorectal (CCR), tellenque la détection d'un changement de l'état d'expression ou de méthylation ou une combinaison correspondante d'un ou de plusieurs gènes parmi un certain nombre. Sont également décrits des procédés pharmacogénétiques pour déterminer des régimes de traitement appropriés pour le cancer et des procédés pour traiter des patients atteints d'un cancer, sur la base de sélection des patients selon les procédés divulgués.
Latest bibliographic data on file with the International Bureau