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1. WO2022003530 - NEUTRALIZING ANTIBODIES TO SARS CORONAVIRUS-2

Publication Number WO/2022/003530
Publication Date 06.01.2022
International Application No. PCT/IB2021/055755
International Filing Date 28.06.2021
IPC
C07K 16/10 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
08against material from viruses
10from RNA viruses
A61K 39/42 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
42viral
A61P 31/14 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
A61P 11/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
G01N 33/68 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
Applicants
  • FONDAZIONE TOSCANA LIFE SCIENCES [IT]/[IT]
Inventors
  • ANDREANO, Emanuele
  • KABANOVA, Anna
  • CARDAMONE, Dario
  • DE SANTI, Concetta
  • PACIELLO, Ida
  • MANGANARO, Noemi
  • PANTANO, Elisa
  • PILERI, Piero
  • SALA, Claudia
  • RAPPUOLI, Rino
  • TROISI, Marco
  • VACCA, Fabioa
Agents
  • DI GIOVINE, Paolo
Priority Data
10202000001575430.06.2020IT
10202000001895503.08.2020IT
10202000002996904.12.2020IT
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) NEUTRALIZING ANTIBODIES TO SARS CORONAVIRUS-2
(FR) ANTICORPS NEUTRALISANTS DIRIGÉS CONTRE LE CORONAVIRUS 2 DU SARS
Abstract
(EN) The present invention relates to monoclonal antibodies or antigen-binding portion thereof that have a potent neutralizing activity against Coronavirus, in particular against SARS-CoV-2. The invention relates also to the use of such monoclonal antibodies or antigen-binding portion thereof in therapy, prophylaxis, and diagnosis of Coronavirus, in particular SARS-CoV-2 dependent diseases.
(FR) La présente invention concerne des anticorps monoclonaux ou une partie de liaison à l'antigène de ceux-ci qui ont une puissante activité de neutralisation contre le coronavirus, en particulier contre le SARS-CoV-2. L'invention concerne également l'utilisation de tels anticorps monoclonaux ou de leur partie de liaison à l'antigène dans la thérapie, la prophylaxie et le diagnostic du coronavirus, en particulier de maladies dépendant du SARS-CoV-2.
Latest bibliographic data on file with the International Bureau