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1. WO2022002988 - TAU BINDING MOLECULES

Publication Number WO/2022/002988
Publication Date 06.01.2022
International Application No. PCT/EP2021/067929
International Filing Date 29.06.2021
IPC
C07K 16/18 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
C07K 7/06 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04Linear peptides containing only normal peptide links
06having 5 to 11 amino acids
C07K 7/08 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04Linear peptides containing only normal peptide links
08having 12 to 20 amino acids
G01N 33/68 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
Applicants
  • GEN2 NEUROSCIENCE LIMITED [GB]/[GB]
Inventors
  • LIVESEY, Frederick
  • JONES, Clare
Agents
  • BATES, Rosica
Priority Data
2009930.529.06.2020GB
2020754.430.12.2020GB
PCT/EP2020/06831429.06.2020EP
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) TAU BINDING MOLECULES
(FR) MOLÉCULES DE LIAISON À TAU
Abstract
(EN) The invention relates to isolated recombinant peptides comprising an epitope from human tau 2N4R. The invention also relates to antibodies, specific for isolated recombinant peptides comprising an epitope from human tau 2N4R and to such antibodies for use in investigation, diagnosis and treatment of tauopathies, such as Alzheimer's disease.
(FR) L'invention concerne des peptides recombinants isolés comprenant un épitope provenant de la protéine humaine tau 2N4R. L'invention concerne également des anticorps, spécifiques de peptides recombinants isolés comprenant un épitope provenant de la protéine tau 2N4R humaine et de tels anticorps destinés à être utilisés dans la recherche, le diagnostic et le traitement de tauopathies, telles que la maladie d'Alzheimer.
Latest bibliographic data on file with the International Bureau