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1. WO2022002854 - A PHOTOABSORBING AGENT FOR THE USE IN AN OPTOACOUSTIC IMAGING METHOD OF A LIVING ORGANISM PROVIDING 2D- OR 3D OPTOACOUSTIC IMAGES, 2D- OR 3D BLOOD FLOW AND LIGHT FLUENCE IMAGES

Publication Number WO/2022/002854
Publication Date 06.01.2022
International Application No. PCT/EP2021/067705
International Filing Date 28.06.2021
IPC
A61B 5/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
A61B 5/0275 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
02Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
026Measuring blood flow
0275using tracers, e.g. dye dilution
A61B 5/0285 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
02Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
026Measuring blood flow
0285Measuring phase velocity of blood waves
Applicants
  • UNIVERSITÄT ZÜRICH [CH]/[CH]
Inventors
  • DEÁN-BEN, Xosé Luís
  • RAZANSKY, Daniel
Agents
  • KLEINE, Hubertus
  • DANTZ, Jan
  • SPECHT, Peter
Priority Data
20183260.730.06.2020EP
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) A PHOTOABSORBING AGENT FOR THE USE IN AN OPTOACOUSTIC IMAGING METHOD OF A LIVING ORGANISM PROVIDING 2D- OR 3D OPTOACOUSTIC IMAGES, 2D- OR 3D BLOOD FLOW AND LIGHT FLUENCE IMAGES
(FR) AGENT PHOTOABSORBANT POUR UTILISATION DANS UN PROCÉDÉ D’IMAGERIE OPTOACOUSTIQUE D’UN ORGANISME VIVANT FOURNISSANT DES IMAGES OPTOACOUSTIQUES 2D OU 3D, DES IMAGES DE FLUX SANGUIN 2D OU 3D ET DE FLUENCE LUMINEUSE
Abstract
(EN) A photoabsorbing agent for the use in an optoacoustic tomography method of a living organism, wherein said agent is an emulsion containing liquid and/or solid particles being at least 2 µm and having a maximum diameter lower than 10 µm and wherein the particles comprise at least an absorbing substance, wherein the molar concentration of the photoabsorbing substance in or at the particles is at least 50 mM or an equivalent amount of g/l; and an optoacoustic tomography method of a living organism providing 2D- or 3D optoacoustic images, 2D- or 3D blood flow and light fluence images.
(FR) La présente invention concerne un agent photoabsorbant pour utilisation dans un procédé de tomographie optoacoustique d’un organisme vivant, ledit agent étant une émulsion contenant des particules liquides et/ou solides étant d’au moins 2 µm et ayant un diamètre maximal inférieur à 10 µm et les particules comprenant au moins une substance absorbante, la concentration molaire de la substance photoabsorbante dans ou au niveau des particules étant d’au moins 50 mM ou une quantité équivalente en g/l ; et un procédé de tomographie optoacoustique d’un organisme vivant fournissant des images optoacoustiques 2D ou 3D, des images de flux sanguin 2D ou 3D et de fluence lumineuse.
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