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1. WO2022002802 - HSV gEgI HETERODIMER ANTIBODIES

Publication Number WO/2022/002802
Publication Date 06.01.2022
International Application No. PCT/EP2021/067584
International Filing Date 25.06.2021
IPC
C07K 16/08 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
08against material from viruses
A61P 31/22 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
20for DNA viruses
22for herpes viruses
CPC
A61P 31/22
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
20for DNA viruses
22for herpes viruses
C07K 16/087
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
08against material from viruses
081from DNA viruses
085Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
087Herpes simplex virus
C07K 2317/34
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
30characterized by aspects of specificity or valency
34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
C07K 2317/92
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
90characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
C07K 2317/94
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
90characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
94Stability, e.g. half-life, pH, temperature or enzyme-resistance
G01N 2333/035
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2333Assays involving biological materials from specific organisms or of a specific nature
005from viruses
01DNA viruses
03Herpetoviridae, e.g. pseudorabies virus
035Herpes simplex virus I or II
Applicants
  • GLAXOSMITHKLINE BIOLOGICALS SA [BE]/[BE]
Inventors
  • DEWAR, Vincent
Agents
  • WEST, Heloise
Priority Data
20182920.729.06.2020EP
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) HSV gEgI HETERODIMER ANTIBODIES
(FR) ANTICORPS HÉTÉRODIMÈRES DE VHS GEGL
Abstract
(EN) The present invention relates to antigen binding protein, and in particular monoclonal antibodies, with bind to a HSV gEgI heterodimer, and to the use of such in detection and potency assays or in therapy.
(FR) La présente invention concerne une protéine de liaison à l'antigène, et en particulier des anticorps monoclonaux se liant à un hétérodimère de VHS gEgI, et l'utilisation de tels dosages de détection et de capacité ou en thérapie.
Latest bibliographic data on file with the International Bureau