Processing

Please wait...

Settings

Settings

Goto Application

1. WO2022002270 - PYRIMIDINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF

Publication Number WO/2022/002270
Publication Date 06.01.2022
International Application No. PCT/CN2021/104379
International Filing Date 02.07.2021
IPC
C07D 401/14 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
14containing three or more hetero rings
A61K 31/506 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
506not condensed and containing further heterocyclic rings
A61K 45/06 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61P 35/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 35/02 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
02specific for leukemia
A61P 31/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
Applicants
  • 盛世泰科生物医药技术(苏州)有限公司 CGENETECH (SUZHOU, CHINA) CO., LTD. [CN]/[CN]
Inventors
  • 余强 YU, Qiang
  • 丁炬平 DING, Juping
  • 汤木林 TANG, Mulin
  • 郝岩 HAO, Yan
  • 卢芹 LU, Qin
  • 钱申 QIAN, Shen
  • 田旭升 TIAN, Xusheng
Agents
  • 北京悦和知识产权代理有限公司 BEIJING YUEHE INTELLECTUAL PROPERTY AGENCY CO., LTD
Priority Data
202010629992.X03.07.2020CN
Publication Language Chinese (zh)
Filing Language Chinese (ZH)
Designated States
Title
(EN) PYRIMIDINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF
(FR) DÉRIVÉ DE PYRIMIDINE, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION
(ZH) 一种嘧啶类衍生物及其制备方法和应用
Abstract
(EN) The present application relates to a pyrimidine derivative, and a preparation method therefor and the use thereof. The pyrimidine derivative is selected from a compound represented by general formula (I) or a tautomer, enantiomer, diastereomer, mesoisomer, racemate or mixture thereof, or a pharmaceutically acceptable salt or prodrug thereof. The pyrimidine derivative exhibits excellent CDK-inhibiting effects.
(FR) La présente invention concerne un dérivé de pyrimidine, son procédé de préparation et son utilisation. Le dérivé de pyrimidine est choisi parmi un composé représenté par la formule générale (I) ou un tautomère, un énantiomère, un diastéréoisomère, un mésoisomère, un racémate ou un mélange de ceux-ci, ou un promédicament ou sel pharmaceutiquement acceptable de celui-ci. Le dérivé de pyrimidine présente d'excellents effets inhibiteurs de la CDK.
(ZH) 本申请涉及一种嘧啶类衍生物及其制备方法和应用,所述嘧啶类衍生物选自:通式(I)所示的化合物或其互变异构体、对映异构体、非对映异构体、内消旋体、外消旋体或其混合物形式,或其可药用盐或其前体药物。该嘧啶类衍生物表现出优异的抑制CDK的效果和作用。
Related patent documents
Latest bibliographic data on file with the International Bureau