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1. WO2022001649 - PREPARATION METHOD FOR LEVETIRACETAM INTERMEDIATE

Publication Number WO/2022/001649
Publication Date 06.01.2022
International Application No. PCT/CN2021/100021
International Filing Date 15.06.2021
IPC
C07D 207/27 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
207Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
02with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
18having one double bond between ring members or between a ring member and a non-ring member
22with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
24Oxygen or sulfur atoms
262-Pyrrolidones
263with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
27with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
Applicants
  • 浙江华海药业股份有限公司 ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD. [CN]/[CN]
Inventors
  • 郑晨光 ZHENG, Chenguang
  • 李敏勇 LI, Minyong
  • 龚玉龙 GONG, Yulong
  • 朱元勋 ZHU, Yuanxun
  • 颜峰峰 YAN, Fengfeng
Agents
  • 北京柏杉松知识产权代理事务所(普通合伙) PATENTSINO IP FIRM
Priority Data
202010612071.230.06.2020CN
Publication Language Chinese (zh)
Filing Language Chinese (ZH)
Designated States
Title
(EN) PREPARATION METHOD FOR LEVETIRACETAM INTERMEDIATE
(FR) PROCÉDÉ DE PRÉPARATION D'INTERMÉDIAIRE DU LÉVÉTIRACÉTAM
(ZH) 一种左乙拉西坦中间体的制备方法
Abstract
(EN) A preparation method for α-ethyl-2-oxo-1-pyrrolidine acetate, and in particular, significantly improving reaction yield and product purity by optimizing a post-treatment process.
(FR) Procédé de préparation d'acétate d'alpha-éthyl-2-oxo-1-pyrrolidine améliorant significativement le rendement de la réaction et la pureté du produit en optimisant un procédé de post-traitement.
(ZH) 一种制备α-乙基-2-氧代-1-吡咯烷乙酸酯的方法,特别是通过优化后处理过程,使反应收率和产品纯度得到显著提升。
Latest bibliographic data on file with the International Bureau