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1. WO2022001071 - METHOD FOR CULTURING CELLS BY USING RING RAIL SHAKING-TYPE BIOREACTOR

Publication Number WO/2022/001071
Publication Date 06.01.2022
International Application No. PCT/CN2020/141987
International Filing Date 31.12.2020
IPC
C12N 5/10 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
10Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
C12N 5/071 2010.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07Animal cells or tissues
071Vertebrate cells or tissues, e.g. human cells or tissues
C12M 3/00 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
C12M 1/36 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
36including condition or time responsive control, e.g. automatically controlled fermentors
Applicants
  • 广州汉腾生物科技有限公司 GUANGZHOU CANTONBIO CO., LTD. [CN]/[CN]
  • 佛山汉腾生物科技有限公司 FOSHAN CANTON BIOLOGICS CO., LTD [CN]/[CN]
  • 佛山普津生物技术有限公司 PROGENBIO CO., LTD. [CN]/[CN]
Inventors
  • 景涛 JING, Tao
  • 陆金康 LU, Jinkang
  • 吴小波 WU, Xiaobo
  • 胡飞 HU, Fei
Agents
  • 广州华进联合专利商标代理有限公司 ADVANCE CHINA IP LAW OFFICE
Priority Data
202010618579.330.06.2020CN
Publication Language Chinese (zh)
Filing Language Chinese (ZH)
Designated States
Title
(EN) METHOD FOR CULTURING CELLS BY USING RING RAIL SHAKING-TYPE BIOREACTOR
(FR) PROCÉDÉ DE CULTURE DE CELLULES AU MOYEN D'UN BIORÉACTEUR DE TYPE AGITATEUR À RAIL ANNULAIRE
(ZH) 一种使用环轨摇晃式生物反应器培养细胞的方法
Abstract
(EN) Provided is a method for culturing cells by using a ring rail shaking-type bioreactor. By means of adjusting conditions such as rotating speed, temperature, and pH value during cell culture, a relatively high cell viability is maintained for a long time, the culture time is prolonged, and the protein expression quantity is increased.
(FR) L'invention concerne un procédé de culture de cellules à l'aide d'un bioréacteur de type agitateur à rail annulaire. En ajustant les conditions telles que la vitesse de rotation, la température et la valeur du pH pendant la culture cellulaire, une viabilité cellulaire relativement élevée est maintenue pendant une longue période, la durée de culture est prolongée et la quantité d'expression des protéines est augmentée.
(ZH) 提供了一种使用环轨摇晃式生物反应器培养细胞的方法,通过调整细胞培养中的转速、温度和pH值等条件,长时间保持较高的细胞活率,延长培养时间,提高蛋白表达量。
Latest bibliographic data on file with the International Bureau