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1. WO2022000807 - ANTI-SKIN PHOTOAGING COMPOSITION AND USE THEREOF

Publication Number WO/2022/000807
Publication Date 06.01.2022
International Application No. PCT/CN2020/116113
International Filing Date 18.09.2020
IPC
A61K 8/63 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
63Steroids; Derivatives thereof
A61K 8/36 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
33containing oxygen
36Carboxylic acids; Salts or anhydrides thereof
A61K 31/575 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
575substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
A61K 8/86 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
72containing organic macromolecular compounds
84obtained by reactions other than those involving only carbon-to-carbon unsaturated bonds
86Polyethers
A61K 8/92 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products
A61Q 19/08 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19Preparations for care of the skin
08Anti-ageing preparations
Applicants
  • 中南大学 CENTRAL SOUTH UNIVERSITY [CN]/[CN]
Inventors
  • 周应军 ZHOU, Yingjun
  • 李丹 LI, Dan
  • 李吉 LI, Ji
  • 曾光尧 ZENG, Guangyao
  • 邓旭 DENG, Xu
  • 曹伟 CAO, Wei
Agents
  • 广州嘉权专利商标事务所有限公司 JIAQUAN IP LAW
Priority Data
202010633773.902.07.2020CN
Publication Language Chinese (zh)
Filing Language Chinese (ZH)
Designated States
Title
(EN) ANTI-SKIN PHOTOAGING COMPOSITION AND USE THEREOF
(FR) COMPOSITION ANTI-PHOTOVIEILLISSEMENT DE LA PEAU ET SON UTILISATION
(ZH) 一种抗皮肤光老化的组合物及其应用
Abstract
(EN) An anti-skin photoaging composition and use thereof. Said composition comprises (0.1 to 100) parts by weight of component A and (1000 to 20000) parts by weight of component B. The component A comprises at least one of carnosic acid, a pharmaceutically acceptable salt thereof or a solvate thereof, and the component B comprises at least one of protopanoxadiol, a pharmaceutically acceptable salt thereof or a solvate thereof. The anti-skin photoaging composition has effects of photoaging resistance and aging resistance. Carnosic acid and protopanoxadiol in the composition act on different antioxidant channels and sites, and achieve a better photoaging resistance effect by means of a synergistic effect. Therefore, the composition is more valuable for promotion and application in skin care products and other products.
(FR) L'invention concerne une composition anti-photovieillissement de la peau et son utilisation. Ladite composition comprend (0,1 à 100) parties en poids du composant A et (1000 à 20000) parties en poids du composant B. Le composant A comprend au moins l'un de l'acide carnosique, un sel pharmaceutiquement acceptable de celui-ci ou un solvate de celui-ci, et le composant B comprend au moins l'un parmi le protopanaxadiol, un sel pharmaceutiquement acceptable de celui-ci ou un solvate de celui-ci. La composition de anti-photovieillissement de la peau a des effets de résistance au photovieillissement et de résistance au vieillissement. L'acide carnosique et le protopanaxadiol dans la composition agissent sur différents canaux et sites antioxydants, et permettent d'obtenir un meilleur effet de résistance au photovieillissement au moyen d'un effet synergique. Par conséquent, la composition est plus intéressante pour la promotion et l'application dans des produits de soin de la peau et d'autres produits.
(ZH) 一种抗皮肤光老化的组合物及其应用,所述组合物包括以重量份计为(0.1~100)份的组分A和(1000~20000)份的组分B,其中,所述组分A包括鼠尾草酸、其药学上可接受的盐或其溶剂化物中的至少一种,所述组分B包括原人参二醇、其药学上可接受的盐或其溶剂化物中的至少一种。该抗皮肤光老化的组合物具有抗光老化和抗衰老的作用,组合物中的鼠尾草酸与原人参二醇作用于不同的抗氧化通道及位点,通过协同作用达到更好的抗光老化效果,因此,该组合物在护肤品等产品中更具有推广应用的价值。
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