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1. WO2021247688 - NANOBODY (VHH) CONJUGATES AND USES THERE OF

Publication Number WO/2021/247688
Publication Date 09.12.2021
International Application No. PCT/US2021/035428
International Filing Date 02.06.2021
IPC
C07K 16/28 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
A61K 39/395 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C12N 5/078 2010.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07Animal cells or tissues
071Vertebrate cells or tissues, e.g. human cells or tissues
078Cells from blood or from the immune system
A61K 47/68 2017.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
68the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
Applicants
  • CHILDREN'S MEDICAL CENTER COPRORATION [US]/[US]
Inventors
  • PISHESHA, Novalia
  • PLOEGH, Hidde L.
  • HARMAND, Thibault
Agents
  • GE, Zhiyun
  • ALAM, Saad
  • AMUNDSEN, Eric, L.
  • ATTISHA, Michael, J.
  • BAKER, C., Hunter
Priority Data
63/033,71002.06.2020US
63/154,45526.02.2021US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) NANOBODY (VHH) CONJUGATES AND USES THERE OF
(FR) CONJUGUÉS DE NANOCORPS (VHH) ET LEURS UTILISATIONS
Abstract
(EN) Provided herein are compositions comprising VHH conjugates and their uses in treating diseases.
(FR) L'invention concerne des compositions comprenant des conjugués VHH et leurs utilisations dans le traitement de maladies.
Latest bibliographic data on file with the International Bureau