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1. WO2021247457 - METHODS FOR MAKING EXTRACELLULAR VESICLES AND USES THEREOF

Publication Number WO/2021/247457
Publication Date 09.12.2021
International Application No. PCT/US2021/035072
International Filing Date 31.05.2021
IPC
C07K 16/00 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
G01N 33/53 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
A61K 9/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
CPC
C07K 16/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
C07K 2317/10
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
10characterized by their source of isolation or production
C07K 2317/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
10characterized by their source of isolation or production
14Specific host cells or culture conditions, e.g. components, pH or temperature
G01N 33/5076
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
5005involving human or animal cells
5008for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
5076involving cell organelles, e.g. Golgi complex, endoplasmic reticulum
G01N 33/6854
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
6854Immunoglobulins
Applicants
  • GENENTECH, INC. [US]/[US]
Inventors
  • KOERBER, James Thomas
  • SUN, Yonglian
Agents
  • LENDARIS, Steven P.
  • PIRRAGLIA, Carolyn
Priority Data
63/033,01401.06.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) METHODS FOR MAKING EXTRACELLULAR VESICLES AND USES THEREOF
(FR) PROCÉDÉS DE PRÉPARATION DE VÉSICULES EXTRACELLULES ET LEURS UTILISATIONS
Abstract
(EN) The present disclosure relates to improved methods and compositions for making extracellular vesicles (EVs). The present disclosure also relates to novel EV-based ELISA assays and kits for performing such assays, as well as methods of producing antibodies to particular antigens using EVs comprising membrane-bound antigen.
(FR) La présente divulgation porte sur des procédés et des compositions améliorés pour la préparation de vésicules extracellulaires (VE). La présente divulgation porte également sur de nouveaux dosages ELISA à base de VE et des kits pour réaliser de tels dosages, ainsi que des procédés de production d'anticorps contre des antigènes particuliers faisant intervenir des VE comprenant un antigène lié à une membrane.
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