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1. WO2021245703 - STABLE LIQUID COMPOSITIONS OF POSACONAZOLE

Publication Number WO/2021/245703
Publication Date 09.12.2021
International Application No. PCT/IN2021/050542
International Filing Date 04.06.2021
IPC
A61K 31/497 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
4965Non-condensed pyrazines
497containing further heterocyclic rings
A61K 31/715 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
Applicants
  • INVENTIA HEALTHCARE LIMITED [IN]/[IN]
Inventors
  • SHAH, Vaibhavi
  • SANKALIA, Mayurbhai
  • BORHADE, Pradnya
Priority Data
20202102377406.06.2020IN
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) STABLE LIQUID COMPOSITIONS OF POSACONAZOLE
(FR) COMPOSITIONS LIQUIDES STABLES DE POSACONAZOLE
Abstract
(EN) The present invention relates to stable, room-temperature storable, liquid compositions comprising posaconazole. The liquid compositions, when stored at room temperature conditions, exhibit no significant coloration and no significant loss in chemical stability. The liquid compositions also exhibit good dilution stability with no evidence of precipitation. The present invention also provides a process for the preparation of such liquid compositions.
(FR) La présente invention concerne des compositions liquides stables, stockables à température ambiante, comprenant du posaconazole. Les compositions liquides, lorsqu'elles sont stockées dans des conditions de température ambiante, ne présentent aucune coloration significative et aucune perte significative de stabilité chimique. Les compositions liquides présentent également une bonne stabilité de dilution sans preuve de précipitation. La présente invention concerne également un procédé de préparation de telles compositions liquides.
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