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1. WO2021242422 - SYSTEMS AND METHODS FOR CONTROL OF REFRACTIVE INDEX AND OPTICAL PROPERTIES IN LIVING BIOLOGICAL CELLS

Publication Number WO/2021/242422
Publication Date 02.12.2021
International Application No. PCT/US2021/026920
International Filing Date 12.04.2021
IPC
C07K 14/435 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
C12N 5/071 2010.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07Animal cells or tissues
071Vertebrate cells or tissues, e.g. human cells or tissues
C12N 13/00 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
13Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
CPC
C12N 5/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor;
C12Q 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
Applicants
  • THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US]/[US]
Inventors
  • GORODETSKY, Alon A.
  • CHATTERJEE, Atrouli
  • CERNA SANCHEZ, Juana Alejandra
Agents
  • HANS, Christian S.
Priority Data
63/008,47410.04.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) SYSTEMS AND METHODS FOR CONTROL OF REFRACTIVE INDEX AND OPTICAL PROPERTIES IN LIVING BIOLOGICAL CELLS
(FR) SYSTÈMES ET PROCÉDÉS DE RÉGULATION DE L'INDICE DE RÉFRACTION ET DES PROPRIÉTÉS OPTIQUES DANS DES CELLULES BIOLOGIQUES VIVANTES
Abstract
(EN) The description of living biological cells comprising heterologously expressed reflectin biomolecules that can be used to dynamically tune the optical properties of the host cells, as well as of the methods of fabrication thereof, are provided. Methods of regulating optical properties, including local refractive indices, of such cells with external stimuli are also provided.
(FR) L'invention concerne la description de cellules biologiques vivantes comprenant des biomolécules de réflectine exprimées de manière hétérologue qui peuvent être utilisées pour ajuster dynamiquement les propriétés optiques des cellules hôtes, ainsi que des procédés de fabrication de celles-ci. L'invention concerne également des procédés de régulation des propriétés optiques, y compris des indices de réfraction locaux, de telles cellules à l'aide de stimuli externes.
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