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1. WO2021234160 - ACE2-FC FUSION PROTEINS AND USES THEREOF

Publication Number WO/2021/234160
Publication Date 25.11.2021
International Application No. PCT/EP2021/063692
International Filing Date 21.05.2021
IPC
A61P 31/14 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
C12N 9/48 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14Hydrolases (3.)
48acting on peptide bonds, e.g. thromboplastin, leucine aminopeptidase (3.4)
A61K 38/48 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
43Enzymes; Proenzymes; Derivatives thereof
46Hydrolases (3)
48acting on peptide bonds (3.4)
A61P 9/12 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
12Antihypertensives
A61P 11/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 13/12 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13Drugs for disorders of the urinary system
12of the kidneys
Applicants
  • FORMYCON AG [DE]/[DE]
Inventors
  • REITER, Alwin
  • BROCKMEYER, Carsten
  • WOLSCHIN, Florian
Agents
  • MAIWALD PATENTANWALTS- UND RECHTSANWALTSGESELLSCHAFT MBH
Priority Data
20176139.222.05.2020EP
20204774.229.10.2020EP
20210297.627.11.2020EP
21164684.924.03.2021EP
21170519.926.04.2021EP
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) ACE2-FC FUSION PROTEINS AND USES THEREOF
(FR) PROTÉINES DE FUSION D'ACE2 ET LEURS UTILISATIONS
Abstract
(EN) The present invention relates to fusion proteins of ACE2 with IgG Fc and the medical use of these fusion proteins, in particular in the prevention or treatment of infections with coronaviruses such as SARS-CoV-2.
(FR) La présente invention concerne des protéines de fusion d'ACE2 avec IgG Fc et l'utilisation médicale de ces protéines de fusion, en particulier dans la prévention ou le traitement d'infections par des coronavirus tels que le SARS-CoV-2.
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