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1. WO2021220792 - ANTIBACTERIAL AGENT

Publication Number WO/2021/220792
Publication Date 04.11.2021
International Application No. PCT/JP2021/015238
International Filing Date 13.04.2021
IPC
A61K 36/9068 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
88Liliopsida (monocotyledons)
906Zingiberaceae (Ginger family)
9068Zingiber, e.g. garden ginger
A61K 33/06 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33Medicinal preparations containing inorganic active ingredients
06Aluminium, calcium or magnesium; Compounds thereof
A61K 36/17 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
17Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
A61K 36/23 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
A61K 36/232 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
232Angelica
A61K 36/233 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
233Bupleurum
CPC
A61K 33/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33Medicinal preparations containing inorganic active ingredients
06Aluminium, calcium or magnesium; Compounds thereof ; , e.g. clay
A61K 36/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
A61K 36/17
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
17Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
A61K 36/23
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
A61K 36/232
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
232Angelica
A61K 36/233
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
233Bupleurum
Applicants
  • 小林製薬株式会社 KOBAYASHI PHARMACEUTICAL CO., LTD. [JP]/[JP]
Inventors
  • 赤木 淳二 AKAGI Junji
  • 大森 公貴 OOMORI Kouki
Priority Data
2020-07955228.04.2020JP
Publication Language Japanese (ja)
Filing Language Japanese (JA)
Designated States
Title
(EN) ANTIBACTERIAL AGENT
(FR) AGENT ANTIBACTÉRIEN
(JA) 抗菌剤
Abstract
(EN) [Problem] The purpose of the present invention is to provide an antibacterial agent that exhibits a selective antibacterial action versus a target bacterium, while not exhibiting an antibacterial action for Staphylococcus aureus in the indigenous condition. [Solution] An antibacterial agent contains an extract of a Chinese herbal medicine (kampo) selected from the group consisting of shin'iseihaito, keigairengyoto, kakkontokasenkyusini, and syoseiryuto, wherein each of these extracts is used in a prescribed dose. The antibacterial agent exhibits a selective antibacterial action versus a target bacterium, but does not exhibit an antibacterial action for Staphylococcus aureus in the indigenous condition.
(FR) Le problème décrit par la présente invention est de fournir un agent antibactérien qui fait preuve d’une action antibactérienne sélective versus une bactérie cible, sans faire preuve d’action antibactérienne contre le Staphylococcus aureus à l’état indigène. La solution selon l’invention porte sur un agent antibactérien contenant un extrait d’un médicament à base d’herbe médicinale chinoise (kampo) sélectionné dans le groupe constitué de shin’iseihaito, keigairengyoto, kakkontokasenkyusini, et syoseiryuto, chacun de ces extraits étant utilisé selon une dose prescrite. L’agent antibactérien fait preuve d’une action antibactérienne sélective versus une bactérie cible, mais ne fait pas preuve d’action antibactérienne contre le Staphylococcus aureus à l’état indigène.
(JA) 【課題】本発明は、常在状態の黄色ブドウ球菌に対する抗菌性を示さず、標的の菌に対する選択的抗菌性を示す抗菌剤を提供することを目的とする。 【解決手段】辛夷清肺湯、荊芥連翹湯、葛根湯加川きゅう辛夷、及び小青竜湯からなる群より選択される漢方のエキスを含有し、それぞれのエキスが所定用量で用いられる抗菌剤は、常在状態の黄色ブドウ球菌に対する抗菌性を示さず、標的の菌に対する選択的抗菌性を示す。
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