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1. WO2021092200 - BIOSYNTHESIS OF CHEMICALLY DIVERSIFIED NON-NATURAL TERPENE PRODUCTS

Publication Number WO/2021/092200
Publication Date 14.05.2021
International Application No. PCT/US2020/059144
International Filing Date 05.11.2020
IPC
A61K 31/035 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
02Halogenated hydrocarbons
035having aliphatic unsaturation
A61K 31/66 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
66Phosphorus compounds
A61K 31/6615 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
66Phosphorus compounds
661Phosphorus acids or esters thereof not having P-C bonds, e.g. fosfosal, dichlorvos, malathion
6615Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
Applicants
  • BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY [US]/[US]
Inventors
  • ELLSWORTH, Edmund
  • GILETTO, Matthew
  • HAMBERGER, Björn
  • MILLER, Garret
  • NEUBIG, Richard
Agents
  • PERDOK, Monique M.
  • ARORA, Suneel
  • BEEKMAN, Marvin L.
  • BIANCHI, Timothy E.
  • BLACK, David W.
  • MCCRACKIN, Ann M.
  • SCHEER, Bradley W.
  • LANG, Allen R.
Priority Data
62/930,89805.11.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) BIOSYNTHESIS OF CHEMICALLY DIVERSIFIED NON-NATURAL TERPENE PRODUCTS
(FR) BIOSYNTHÈSE DE PRODUITS TERPÉNIQUES NON NATURELS DIVERSIFIÉS CHIMIQUEMENT
Abstract
(EN)
The disclosure relates to compounds of the formulae (l)-(IV) and their use as substrates for making terpenoids. New substrates for terpene biosynthesis and methods for making new types of terpenes are described herein. Diterpenes occupy a unique molecular space with critical pharmaceutical applications over a diverse spectrum including anti-microbial, anti-cancer, immunomodulatory and psychoactive properties.
(FR)
La divulgation concerne des composés représentés par les formules (I)-(IV) et leur utilisation en tant que substrats pour la fabrication de terpénoïdes. L'invention concerne également de nouveaux substrats pour la biosynthèse de terpènes et des procédés de fabrication de nouveaux types de terpènes. Les diterpènes occupent un espace moléculaire unique avec des applications pharmaceutiques importantes sur un large spectre et présentent des propriétés antimicrobiennes, anti-cancéreuses, immunomodulatrices et psychoactives.
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