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1. WO2021091958 - RIG-I INNATE IMMUNE RECEPTOR ANTAGONISTS AND METHODS OF USING SAME

Publication Number WO/2021/091958
Publication Date 14.05.2021
International Application No. PCT/US2020/058803
International Filing Date 04.11.2020
IPC
A61K 31/403 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403condensed with carbocyclic rings, e.g. carbazole
A61K 31/712 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7088Compounds having three or more nucleosides or nucleotides
712Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
Applicants
  • YALE UNIVERSITY [US]/[US]
Inventors
  • PYLE, Anna, Marie
  • RAWLING, David
  • JAGDMANN, G., Erik
  • POTAPOVA, Olga
Agents
  • DOYLE, Kathryn
  • LANDRY, Brian
  • SILVA, Domingos
  • SIMPSON, Mark
  • CROTTY, Justin
  • YOUNG, Jacque
  • BROWNING, Elizabeth
  • OSTROVSKY, Dennis
Priority Data
62/930,02504.11.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) RIG-I INNATE IMMUNE RECEPTOR ANTAGONISTS AND METHODS OF USING SAME
(FR) ANTAGONISTES DU RÉCEPTEUR IMMUNITAIRE INNÉ RIG-I ET LEURS PROCÉDÉS D'UTILISATION
Abstract
(EN)
The present disclosure provides RIG-I antagonists. In certain embodiments, the antagonists of the disclosure can be used to treat or prevent a disease or disorder in a subject.
(FR)
La présente invention concerne des antagonistes RIG-I. Dans certains modes de réalisation, les antagonistes de l'invention peuvent être utilisés pour traiter ou prévenir une maladie ou un trouble chez un sujet.
Latest bibliographic data on file with the International Bureau