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1. WO2021064137 - MULTI-SPECIFIC BINDING PROTEINS FOR CANCER TREATMENT

Publication Number WO/2021/064137
Publication Date 08.04.2021
International Application No. PCT/EP2020/077586
International Filing Date 01.10.2020
IPC
C07K 16/28 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
CPC
A61K 2039/505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
505comprising antibodies
A61K 2039/82
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
80Vaccine for a specifically defined cancer
82Colon
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07K 16/2809
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
2803against the immunoglobulin superfamily
2809against the T-cell receptor (TcR)-CD3 complex
C07K 16/2827
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
2803against the immunoglobulin superfamily
2827against B7 molecules, e.g. CD80, CD86
C07K 2317/24
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
20characterized by taxonomic origin
24containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Applicants
  • BOEHRINGER INGELHEIM INTERNATIONAL GMBH [DE]/[DE]
Inventors
  • HIPP, Susanne
  • ADAM, Paul
  • DZIEGELEWSKI, Michael
  • GANESAN, Rajkumar
  • GORMAN, Philip Nicholas
  • GUPTA, Pankaj
  • GUPTA, Priyanka
  • LASARO, Marcio
  • SCHEER, Justin M.
  • VOYNOV, Vladimir H.
Agents
  • SIMON, Elke Anna Maria
  • WOLFRAM, Dr. Markus
Priority Data
19201200.302.10.2019EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MULTI-SPECIFIC BINDING PROTEINS FOR CANCER TREATMENT
(FR) PROTÉINES DE LIAISON MULTI-SPÉCIFIQUES POUR LE TRAITEMENT DU CANCER
Abstract
(EN)
The present invention relates to novel B7H6/CD3 binding proteins. The invention also relates to nucleic acids encoding such proteins; to methods for preparing such proteins; to host cells expressing or capable of expressing such proteins; to compositions comprising such proteins; and to uses of such proteins or such compositions, in particular for therapeutic purposes in the field of cancer diseases.
(FR)
La présente invention concerne de nouvelles protéines de liaison B7H6/CD3. L'invention concerne également des acides nucléiques codant pour lesdites protéines; des méthodes de préparation de telles protéines; des cellules hôtes exprimant ou pouvant exprimer ces protéines; des compositions comprenant lesdites protéines; et des utilisations de ces protéines ou desdites compositions, en particulier à des fins thérapeutiques dans le domaine des maladies cancéreuses.
Also published as
Latest bibliographic data on file with the International Bureau