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1. WO2021062290 - METHODS OF PRODUCING EXTRACELLULAR VESICLES

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Publication Number WO/2021/062290
Publication Date 01.04.2021
International Application No. PCT/US2020/052901
International Filing Date 25.09.2020
IPC
B01D 15/38 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
15Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
08Selective adsorption, e.g. chromatography
26characterised by the separation mechanism
38involving specific interaction not covered by one or more of groups B01D15/30-B01D15/36120
B01D 15/36 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
15Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
08Selective adsorption, e.g. chromatography
26characterised by the separation mechanism
36involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
CPC
A61K 9/5192
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
50Microcapsules ; having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
51Nanocapsules; Nanoparticles;
5192Processes
B01D 15/363
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
15Separating processes involving the treatment of liquids with solid sorbents
08Selective adsorption, e.g. chromatography
26characterised by the separation mechanism
36involving ionic interaction
361Ion-exchange
363Anion-exchange
B01D 15/3847
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
15Separating processes involving the treatment of liquids with solid sorbents
08Selective adsorption, e.g. chromatography
26characterised by the separation mechanism
38involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
3847Multimodal interactions
Applicants
  • CODIAK BIOSCIENCES, INC. [US]/[US]
Inventors
  • BOURDEAU, Raymond
  • JANG, Su Chul
  • HARRISON, Rane
  • O'NEIL, Conlin
  • NOYES, Aaron
Agents
  • KIM, Ji Eun
  • BANOWIT, Donald R.
  • BEMBEN, Richard M.
  • BEZOS, Salvador M.
  • BLOCK, Daniel S.
  • BODENSTEIN, Matthew S.
  • CALVO, Paul A.
  • CAMARCE, Christian
  • CIMBALA, Michele A.
  • COLLER III, Richard D.
  • CONKLIN, Kyle E.
  • COVERT, John M.
  • DURKIN, Tracy-Gene
  • EISENBERG, Jason D.
  • ELLISON, Eldora L.
  • ESMOND, Robert W.
  • FEATHERSTONE, Donald A.
  • FITZSIMMONS, Jason A.
  • FRUEAUF, Jeremiah B.
  • GAJEWSKI, Daniel A.
  • GILLENTINE, Marsha Rose
  • GOLDSTEIN, Jorge A.
  • HELVEY, Jeffrey T.
  • HICKS, Ross G.
  • HOLOUBEK, Michelle K.
  • JACKMAN, Peter A.
  • KENTON JR., Lestin L.
  • LEE, Michael Q.
  • LONGSWORTH, Gaby L.
  • MILLONIG, Robert C.
  • MUTSCHELKNAUS, Joseph
  • NANNENGA-COMBS, Bonnie W.
  • POWERS III, R. Wilson
  • RAY, Michael B.
  • RICHARDSON, Ryan C.
  • RYGIEL, Mark W.
  • SHEA JR., Timothy J.
  • SOKOHL, Robert E.
  • SPECHT, Michael D.
  • STEFFE, Eric K.
  • STERLING, Deborah A.
  • STERNE, Robert Greene
  • GLENN, Dallin G.
  • HOLMAN, David H.
  • PHERO, Graham C.
Priority Data
62/906,02325.09.2019US
63/059,75431.07.2020US
63/066,65417.08.2020US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS OF PRODUCING EXTRACELLULAR VESICLES
(FR) PROCÉDÉS DE PRODUCTION DE VÉSICULES EXTRACELLULAIRES
Abstract
(EN)
Provided herein are methods of preparing EVs, e.g., exosomes, associated with or encapsulated various cyclic dinucleotides, including STING agonists. Also provided herein are methods of loading EVs, e.g., exosomes, with various cyclic dinucleotides, including STING agonists.
(FR)
L'invention concerne des procédés de préparation de vésicules extracellulaires, par exemple , des exosomes, associés à divers dinucléotides cycliques ou encapsulant ceux-ci, y compris des agonistes de STING. L'invention concerne également des procédés de chargement de vésicules extracellulaires par exemple , des exosomes, avec divers dinucléotides cycliques, y compris des agonistes de STING.
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