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1. WO2021058001 - CRYSTAL FORM OF FIVE-MEMBERED N HETEROCYCLIC COMPOUND, AND APPLICATION THEREOF

Publication Number WO/2021/058001
Publication Date 01.04.2021
International Application No. PCT/CN2020/118426
International Filing Date 28.09.2020
IPC
C07D 207/34 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
207Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
02with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
30having two double bonds between ring members or between ring members and non-ring members
34with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
A61K 31/40 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
A61P 31/20 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
20for DNA viruses
CPC
A61K 31/40
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
A61P 31/20
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
20for DNA viruses
C07D 207/34
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
207Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
02with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
30having two double bonds between ring members or between ring members and non-ring members
34with heteroatoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Applicants
  • 正大天晴药业集团股份有限公司 CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. [CN]/[CN]
Inventors
  • 王普军 WANG, Pujun
  • 郭猛 GUO, Meng
  • 胡明通 HU, Mingtong
  • 吴杰 WU, Jie
  • 敖汪伟 AO, Wangwei
  • 张寅生 ZHANG, Yinsheng
Agents
  • 北京英赛嘉华知识产权代理有限责任公司 INSIGHT INTELLECTUAL PROPERTY LIMITED
Priority Data
201910933542.729.09.2019CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) CRYSTAL FORM OF FIVE-MEMBERED N HETEROCYCLIC COMPOUND, AND APPLICATION THEREOF
(FR) FORME CRISTALLINE DE COMPOSÉ À HÉTÉROCYCLE AZOTÉ À CINQ CHAÎNONS ET SON APPLICATION
(ZH) N杂五元环化合物的晶型及其应用
Abstract
(EN)
Disclosed are a crystal form of a five-membered N heterocyclic compound, particularly, a crystal from of a compound as represented by formula I, and an application of the crystal form in preparation of a medication for preventing or treating a disease that can be alleviated by inhibition of capsid protein assembly.
(FR)
L'invention concerne une forme cristalline d'un composé à hétérocycle azoté à cinq chaînons, en particulier une forme cristalline d'un composé tel que représenté par la formule I, et une application de la forme cristalline dans la préparation d'un médicament pour la prévention ou le traitement d'une maladie qui peut être soulagée par l'inhibition de l'assemblage de protéines capsidiques.
(ZH)
公开了N杂五元环化合物的晶型,具体涉及式I化合物的晶型,还包括所述晶型在制备预防或者治疗受益于衣壳蛋白装配抑制的疾病的药物中的应用。
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