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1. WO2021044008 - Bispecific binding agent that binds to CD117/c-KIT and CD3

Publication Number WO/2021/044008
Publication Date 11.03.2021
International Application No. PCT/EP2020/074807
International Filing Date 04.09.2020
IPC
C07K 16/28 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
C07K 16/24 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
24against cytokines, lymphokines or interferons
C07K 16/46 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
46Hybrid immunoglobulins
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
CPC
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07K 16/24
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
24against cytokines, lymphokines or interferons
C07K 16/28
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
C07K 16/2809
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
2803against the immunoglobulin superfamily
2809against the T-cell receptor (TcR)-CD3 complex
C07K 16/2896
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
2896against molecules with a "CD"-designation, not provided for elsewhere
C07K 16/46
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
46Hybrid immunoglobulins
Applicants
  • UNIVERSITÄT ZÜRICH [CH]/[CH]
  • ETH ZÜRICH [CH]/[CH]
Inventors
  • KIEFER, Jonathan
  • MYBURGH, Renier
  • MANZ, Markus
  • NERI, Dario
Agents
  • MICHALSKI HÜTTERMANN & PARTNER PATENTANWÄLTE MBB
  • DR. STORZ, Ulrich
Priority Data
GB1912681.204.09.2019GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) Bispecific binding agent that binds to CD117/c-KIT and CD3
(FR) AGENT DE LIAISON BISPÉCIFIQUE QUI SE LIE À CD117/C-KIT ET CD3
Abstract
(EN)
The present invention relates to a bispecific binding agent comprising at least a first binding domain and a second binding domain, wherein said first binding domain binds to CD117/c- KIT and wherein said second binding domain binds to CD3 (Fig. 1).
(FR)
La présente invention concerne un agent de liaison bispécifique comprenant au moins un premier domaine de liaison et un second domaine de liaison, ledit premier domaine de liaison se liant à CD117/C-KIT et ledit second domaine de liaison se liant à CD3 (Fig. 1).
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