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1. WO2021042274 - TRADITIONAL CHINESE AND WESTERN MEDICINE COMPOSITION FOR TREATING OSTEOARTHRITIS

Publication Number WO/2021/042274
Publication Date 11.03.2021
International Application No. PCT/CN2019/104248
International Filing Date 03.09.2019
IPC
A61K 36/8994 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
88Liliopsida (monocotyledons)
899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
8994Coix (Job's tears)
A61K 36/808 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
80Scrophulariaceae (Figwort family)
808Scrophularia (figwort)
A61K 36/756 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
75Rutaceae (Rue family)
756Phellodendron, e.g. corktree
A61K 36/71 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
A61K 36/484 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
484Glycyrrhiza (licorice)
A61K 36/481 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
481Astragalus (milkvetch)
CPC
A61K 31/635
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
635having a heterocyclic ring, e.g. sulfadiazine
A61K 35/62
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
56Materials from animals other than mammals
62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
A61K 35/64
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
56Materials from animals other than mammals
63Arthropods
64Insects, e.g. bees, wasps or fleas
A61K 36/232
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
232Angelica
A61K 36/284
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
284Atractylodes
A61K 36/35
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
35Caprifoliaceae (Honeysuckle family)
Applicants
  • 鲁南制药集团股份有限公司 LUNAN PHARMACEUTICAL GROUP CORPORATION [CN]/[CN]
Inventors
  • 李元森 LI, Yuansen
  • 杨本官 YANG, Benguan
Priority Data
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) TRADITIONAL CHINESE AND WESTERN MEDICINE COMPOSITION FOR TREATING OSTEOARTHRITIS
(FR) COMPOSITION DE MÉDECINE OCCIDENTALE ET CHINOISE TRADITIONNELLE POUR LE TRAITEMENT DE L'ARTHROSE
(ZH) 一种治疗骨性关节炎的中西药组合物
Abstract
(EN)
A traditional Chinese and western medicine composition for treating osteoarthritis, being mainly prepared from Astragalus membranaceus, honeysuckle, golden cypress, Atractylodis rhizoma, coix seed, Scrophularia ningpoensis, Angelica sinensis, Radix paeoniae alba, liquorice, hirudo, centipede, scorpion and celecoxib. Animal tests show that the traditional Chinese and western medicine composition has therapeutic effects on joint diseases, especially osteoarthritis, and can reduce inflammatory factors, reduce inflammation, enlarge the movement range of diseased joints, and reduce the swelling thickness of a synovial membrane.
(FR)
L'invention concerne une composition de médecine occidentale et chinoise traditionnelle pour le traitement de l'arthrose, étant principalement préparée à partir d'Astragalus membranaceus, de chèvrefeuille, de faux-cyprès Sawara, de rhizome d'Atractylodis, de graine de coix, de Scrophularia ningpoensis, d'Angelica sinensis, de Radix paeoniae alba, de réglisse, de sangsue, de mille-pattes, de scorpion et de célécoxib. Les tests animaux montrent que la composition de médecine occidentale et chinoise traditionnelle a des effets thérapeutiques sur les maladies articulaires, en particulier l'arthrose, et peut réduire les facteurs inflammatoires, réduire l'inflammation, agrandir la plage de mouvement des articulations malades, et réduire l'épaisseur de gonflement d'une membrane synoviale.
(ZH)
一种治疗骨性关节炎的中西药组合物,其主要由黄芪、金银花、黄柏、苍术、薏苡仁、玄参、当归、白芍、甘草、水蛭、蜈蚣、全蝎、塞来昔布制备而成。动物试验表明,该中西药组合物对关节疾病,尤其是骨性关节炎具有治疗效果,可减少炎症因子、降低炎症反应、扩大病变关节的活动范围、减小滑膜肿胀厚度。
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