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1. WO2021041896 - NOVEL THERANOSTIC AGENTS FOR PSMA POSITIVE CANCERS

Publication Number WO/2021/041896
Publication Date 04.03.2021
International Application No. PCT/US2020/048524
International Filing Date 28.08.2020
IPC
A61K 31/58 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
58containing heterocyclic rings, e.g. aldosterone, danazol, stanozolol, pancuronium, digitogenin
C07J 43/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
43Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopentahydrophenanthrene skeleton
C12Q 1/68 2018.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
CPC
A61K 31/58
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids
58containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
C07J 43/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
43Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
Applicants
  • MEMORIAL SLOAN KETTERING CANCER CENTER [US]/[US]
Inventors
  • PILLARSETTY, Naga Vara Kishore
  • KALIDINDI, Teja Muralidhar
  • LEE, Sang-Gyu
  • LARSON, Steven M.
  • LEWIS, Jason S.
  • LYASHCHENKO, Serge
  • BURNAZI, Eva
Agents
  • MEARA, Joseph P.
  • FERNANDES, Jolene S.
Priority Data
62/894,59430.08.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NOVEL THERANOSTIC AGENTS FOR PSMA POSITIVE CANCERS
(FR) NOUVEAUX AGENTS THÉRANOSTIQUES DESTINÉS AUX CANCERS POSITIFS AU PSMA
Abstract
(EN)
The present disclosure provides compositions and methods for the detection and treatment of cancer. Specifically, the compositions of the present technology include novel radiohalogenated (e.g., radioiodinated) PSMA targeting agents and methods of using the same in diagnostic imaging as well as radiation therapy.
(FR)
La présente invention concerne des compositions et des méthodes pour la détection et le traitement du cancer. Plus particulièrement, les compositions de la présente invention comprennent de nouveaux agents de ciblage de PSMA radiohalogénés (par exemple, radio-iodés) et des méthodes d'utilisation de ceux-ci dans une imagerie diagnostique ainsi qu'une radiothérapie.
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