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1. WO2021037094 - TEMPERATURE CONTROL ON DIGITAL MICROFLUIDICS DEVICE

Publication Number WO/2021/037094
Publication Date 04.03.2021
International Application No. PCT/CN2020/111570
International Filing Date 27.08.2020
IPC
C12M 1/38 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
36including condition or time responsive control, e.g. automatically controlled fermentors
38Temperature-responsive control
C12M 1/34 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
34Measuring or testing with condition measuring or sensing means, e.g. colony counters
C12M 1/00 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
C12Q 1/68 2018.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
CPC
B01L 2200/10
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
10Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
B01L 2200/147
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
14Process control and prevention of errors
143Quality control, feedback systems
147Employing temperature sensors
B01L 2300/0645
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
06Auxiliary integrated devices, integrated components
0627Sensor or part of a sensor is integrated
0645Electrodes
B01L 2300/1822
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
18Means for temperature control
1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
1822using Peltier elements
B01L 2300/1827
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
18Means for temperature control
1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
1827using resistive heater
B01L 2400/0427
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2400Moving or stopping fluids
04Moving fluids with specific forces or mechanical means
0403specific forces
0415electrical forces, e.g. electrokinetic
0427Electrowetting
Applicants
  • BGI SHENZHEN CO., LTD. [CN]/[CN]
Inventors
  • LIN, Yan-You
  • GONG, Jian
  • ZHONG, Frank
Agents
  • SYNCLAW ATTORNEYS
Priority Data
62/893,09128.08.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) TEMPERATURE CONTROL ON DIGITAL MICROFLUIDICS DEVICE
(FR) RÉGULATION DE TEMPÉRATURE SUR DISPOSITIFS MICROFLUIDIQUES NUMÉRIQUES
Abstract
(EN)
A microfluidic device includes first and second substrate structures. The first substrate structure has a first substrate surface configured to receive one or more droplets. A plurality of electrodes configured to apply an electric field to the droplets. The second substrate structure has a second substrate surface facing the first substrate surface and spaced apart from the first substrate surface to form a fluid channel. The microfluidic device has a first heating element adjacent to the first substrate structure and disposed on an opposite side of the first substrate surface, and a second heating element adjacent to the second substrate structure and disposed on an opposite side of the second substrate surface. The microfluidic device further includes one or more temperature sensors disposed adjacent to the fluid channel between the first substrate structure and the second substrate structure.
(FR)
La présente invention concerne un dispositif microfluidique comprenant de première et seconde structures de substrat. La première structure de substrat présente une première surface de substrat conçue pour recevoir une ou plusieurs gouttelettes. Une pluralité d’électrodes conçues pour appliquer un champ électrique aux gouttelettes. La seconde structure de substrat présente une seconde surface de substrat faisant face à la première surface de substrat et espacée de la première surface de substrat pour former un canal de liquide. Le dispositif microfluidique présente un premier élément de chauffage adjacent à la première structure de substrat et disposé sur un côté opposé de la première surface de substrat, et un second élément de chauffage adjacent à la seconde structure de substrat et disposé sur un côté opposé de la seconde surface de substrat. Le dispositif microfluidique comprend en outre un ou plusieurs capteurs de température disposés adjacents au canal de liquide entre la première structure de substrat et la seconde structure de substrat.
Also published as
Latest bibliographic data on file with the International Bureau