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1. WO2021030687 - THERAPEUTIC PEPTIDES

Publication Number WO/2021/030687
Publication Date 18.02.2021
International Application No. PCT/US2020/046375
International Filing Date 14.08.2020
IPC
A61K 38/08 2019.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
08Peptides having 5 to 11 amino acids
A61K 38/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
10Peptides having 12 to 20 amino acids
A61P 3/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
04Anorexiants; Antiobesity agents
Applicants
  • COHBAR, INC. [US]/[US]
Inventors
  • GUNDY, Kenneth
Agents
  • GASS, David A.
Priority Data
62/887,04915.08.2019US
63/035,52105.06.2020US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) THERAPEUTIC PEPTIDES
(FR) PEPTIDES THÉRAPEUTIQUES
Abstract
(EN)
The disclosures herein relate to the fields of cell biology and the modulation of cellular mechanisms controlling cell viability, cell proliferation, and metabolic processes. More specifically disclosed herein are peptides effective to modulate cellular mechanisms controlling cell viability, cell proliferation, and metabolic processes, including cell signaling associated with aberrant cellular proliferation and malignancy. Also disclosed herein are peptides effective in modulating cellular mechanisms controlling cell viability, treating metabolic diseases, and as cytoprotective agents. Also disclosed herein are peptides effective as apelin receptor agonists.
(FR)
L'invention concerne les domaines de la biologie cellulaire et de la modulation de mécanismes cellulaires régulant la viabilité cellulaire, la prolifération cellulaire et les processus métaboliques. Plus spécifiquement, l'invention concerne des peptides efficaces pour moduler des mécanismes cellulaires régulant la viabilité cellulaire, la prolifération cellulaire et des processus métaboliques, comprenant la signalisation cellulaire associée à une prolifération cellulaire aberrante et à une malignité. L'invention concerne également des peptides efficaces dans la modulation de mécanismes cellulaires régulant la viabilité cellulaire, le traitement de maladies métaboliques, et en tant qu'agents cytoprotecteurs. L'invention concerne également des peptides efficaces en tant qu'agonistes du récepteur de l'apeline.
Latest bibliographic data on file with the International Bureau