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1. WO2021030657 - MATERIALS AND METHODS FOR IMPROVED SINGLE CHAIN VARIABLE FRAGMENTS

Publication Number WO/2021/030657
Publication Date 18.02.2021
International Application No. PCT/US2020/046303
International Filing Date 14.08.2020
IPC
C07K 16/18 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
C07K 16/46 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
46Hybrid immunoglobulins
C07K 16/30 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
30from tumour cells
C07K 16/10 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
08against material from viruses
10from RNA viruses
CPC
C07K 16/1027
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
08against material from viruses
10from RNA viruses ; , e.g. hepatitis E virus
1027Paramyxoviridae, e.g. respiratory syncytial virus
C07K 16/18
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
C07K 16/30
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
30from tumour cells
C07K 16/468
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
46Hybrid immunoglobulins
468Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
C07K 2317/622
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
60characterized by non-natural combinations of immunoglobulin fragments
62comprising only variable region components
622Single chain antibody (scFv)
C07K 2317/624
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
60characterized by non-natural combinations of immunoglobulin fragments
62comprising only variable region components
624Disulfide-stabilized antibody (dsFv)
Applicants
  • JANSSEN BIOTECH, INC. [US]/[US]
Inventors
  • LUO, Jinquan
  • BOUCHER, Lauren
  • FELDKAMP, Michael
  • DIEM, Michael
  • ARMSTRONG, Anthony, A.
  • TEPLYAKOV, Alexey
  • HUANG, Chichi
Agents
  • WEISSER, Tamera, M.
  • INSOGNA, Anthony, M.
  • GEORGE, Nikolaos, C.
  • ANTLER, Adriane, M.
  • ROWAN, Thomas, G.
Priority Data
62/887,51415.08.2019US
62/887,51915.08.2019US
62/887,52415.08.2019US
62/887,52715.08.2019US
62/887,52915.08.2019US
62/946,86511.12.2019US
62/946,87711.12.2019US
62/946,88211.12.2019US
62/946,88611.12.2019US
62/946,89711.12.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MATERIALS AND METHODS FOR IMPROVED SINGLE CHAIN VARIABLE FRAGMENTS
(FR) MATÉRIAUX ET PROCÉDÉS POUR DES FRAGMENTS VARIABLES À CHAÎNE UNIQUE AMÉLIORÉS
Abstract
(EN)
Disclosed are materials and methods for improved single chain variable fragments.
(FR)
La présente divulgation concerne des matériaux et des procédés pour des fragments variables à chaîne unique améliorés.
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