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1. WO2021022037 - IL-38-SPECIFIC ANTIOBODIES

Publication Number WO/2021/022037
Publication Date 04.02.2021
International Application No. PCT/US2020/044260
International Filing Date 30.07.2020
IPC
A61K 39/395 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07K 16/24 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
24against cytokines, lymphokines or interferons
Applicants
  • IMMUNOME, INC. [US]/[US]
Inventors
  • ROBINSON, Matthew, K.
  • LUNDGREN, Karen
  • HARMAN, Ben
  • NIKITIN, Pavel, A.
  • DOWLING, John, P.
Agents
  • BELLUM, Stephen, C.
Priority Data
62/880,26530.07.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) IL-38-SPECIFIC ANTIOBODIES
(FR) ANTICORPS SPÉCIFIQUES DE L'IL-38
Abstract
(EN)
This invention relates to antibodies specific for human interleukin-38 (IL-38), including isolated antibodies, or antigen-binding fragments thereof. The antibodies, or antigen-binding fragments thereof, described here partially or fully block, inhibit, or neutralize a biological activity of IL 38. Methods described here relate to inhibiting tumor growth or metastasis in an individual afflicted by tumor growth and/or metastasis.
(FR)
La présente invention concerne des anticorps spécifiques de l'interleukine 38 humaine (IL-38) comprenant des anticorps isolés ou leurs fragments de liaison à l'antigène. Les anticorps ou leurs fragments de liaison à l'antigène susmentionnés bloquent, inhibent ou neutralisent, partiellement ou totalement, une activité biologique de l'IL-38. Les procédés susmentionnés concernent l'inhibition de la croissance tumorale ou de la métastase chez un individu présentant une croissance tumorale et/ou une métastase.
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