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1. WO2021021904 - PHARMACOLOGICAL INHIBITORS OF THE ENL YEATS DOMAIN

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Publication Number WO/2021/021904
Publication Date 04.02.2021
International Application No. PCT/US2020/044030
International Filing Date 29.07.2020
IPC
A61K 38/08 2019.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
08Peptides having 5 to 11 amino acids
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07K 7/06 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04Linear peptides containing only normal peptide links
06having 5 to 11 amino acids
CPC
A61K 31/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
A61K 38/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
08Peptides having 5 to 11 amino acids
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
Applicants
  • THE SCRIPPS RESEARCH INSTITUTE [US]/[US]
Inventors
  • ERB, Michael A.
  • WOLAN, Dennis
  • KITAMURA, Seiya
  • CHATTERJEE, Arnab
Agents
  • PHUKAN, Priti
  • FESSENMAIER, Martin
  • DEAN, Ryan
  • BALLEW CHANG, Nicole
Priority Data
62/880,56430.07.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PHARMACOLOGICAL INHIBITORS OF THE ENL YEATS DOMAIN
(FR) INHIBITEURS PHARMACOLOGIQUES DU DOMAINE ENL YEATS
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Abstract
(EN)
Provided herein are compounds, pharmaceutical compositions, and methods for inhibiting the ENL YEATS domain. Further, provided herein are compounds, pharmaceutical compositions, and methods for the treatment of leukemia.
(FR)
La présente invention concerne des composés, des compositions pharmaceutiques et des procédés d'inhibition du domaine ENL YEATS. La présente invention concerne des composés, des compositions pharmaceutiques et des méthodes de traitement de la leucémie.
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