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1. WO2021011356 - SYSTEMS AND METHODS FOR EVALUATING IMMUNE RESPONSE TO INFECTION

Publication Number WO/2021/011356
Publication Date 21.01.2021
International Application No. PCT/US2020/041548
International Filing Date 10.07.2020
IPC
G01N 33/569 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
569for microorganisms, e.g. protozoa, bacteria, viruses
G01N 33/80 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
80involving blood groups or blood types
CPC
G01N 15/1459
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
10Investigating individual particles
14Electro-optical investigation, e.g. flow cytometers
1456without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
1459the analysis being performed on a sample stream
G01N 2015/0073
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
0065biological, e.g. blood
0073Red blood cells
G01N 2015/1006
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
10Investigating individual particles
1006for cytology
G01N 2800/26
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2800Detection or diagnosis of diseases
26Infectious diseases, e.g. generalised sepsis
G01N 2800/52
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2800Detection or diagnosis of diseases
52Predicting or monitoring the response to treatment; Prognosis
G01N 2800/7095
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2800Detection or diagnosis of diseases
70Mechanisms involved in disease identification
7095Inflammation
Applicants
  • BECKMAN COULTER, INC. [US]/[US]
Inventors
  • TEJIDOR, Liliana
  • MAGARI, Robert T.
  • CAREAGA, Diana
  • SHIN, Sanghyuk
Agents
  • MORRISS, William S.
  • ACHESON, Edwin, R.
  • CONLEY, Scott, R.
  • SCHOEN, Ann, G.
  • KERSTING, Jeffrey, F.
Priority Data
62/873,57512.07.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SYSTEMS AND METHODS FOR EVALUATING IMMUNE RESPONSE TO INFECTION
(FR) SYSTÈMES ET PROCÉDÉS POUR ÉVALUER UNE RÉPONSE IMMUNITAIRE À UNE INFECTION
Abstract
(EN)
Systems and methods for characterizing immune response to infection using cellular analysis, such as a hematological cellular analyzer. In some instances, the immune response may be characterized as normal or abnormal based on one or more blood cell population parameters. In some instances, abnormal characterization may be used to identify patients with sepsis or at elevated risk of developing sepsis.
(FR)
L'invention concerne des systèmes et des procédés pour caractériser une réponse immunitaire à une infection à l'aide d'une analyse cellulaire, notamment à l'aide d'un analyseur cellulaire hématologique. Dans certains cas, la réponse immunitaire peut être caractérisée comme normale ou anormale sur la base d'un ou de plusieurs paramètres de population de cellules sanguines. Dans certains cas, une caractérisation anormale peut être utilisée pour identifier des patients présentant une sepsie ou à un risque élevé de développer une sepsie.
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