Processing

Please wait...

Settings

Settings

Goto Application

1. WO2021011334 - DEUTERATED DERIVATIVES OF 6,8-BIS(BENZYLSULFANYL)OCTANOIC ACID

Publication Number WO/2021/011334
Publication Date 21.01.2021
International Application No. PCT/US2020/041503
International Filing Date 10.07.2020
IPC
C07C 323/56 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
323Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
50containing thio groups and carboxyl groups bound to the same carbon skeleton
51having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
56the carbon skeleton containing six-membered aromatic rings
A61P 35/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 35/02 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
02specific for leukemia
CPC
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 35/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
02specific for leukemia
C07B 2200/05
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
2200Indexing scheme relating to specific properties of organic compounds
05Isotopically modified compounds, e.g. labelled
C07B 59/001
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
59Introduction of isotopes of elements into organic compounds ; ; Labelled organic compounds per se
001Acyclic or carbocyclic compounds
C07C 323/52
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
323Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
50containing thio groups and carboxyl groups bound to the same carbon skeleton
51having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
52the carbon skeleton being acyclic and saturated
C07C 323/56
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
323Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
50containing thio groups and carboxyl groups bound to the same carbon skeleton
51having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
56the carbon skeleton containing six-membered aromatic rings
Applicants
  • RAFAEL PHARMACEUTICALS, INC. [US]/[US]
Inventors
  • BARER, Sol, J.
  • XIN, Yanchao
  • HONG, Yaping
  • ZHOU, Gang
Agents
  • DAVIS, Chad, E.
  • REID, Andrea L.C.
  • NIHAN, Danielle M.
  • ARICO, Joseph W.
  • WANG, Gang
  • OH, Euk Charlie
  • STEVENSON, Christian
  • MANAS, Michael
Priority Data
62/873,44712.07.2019US
63/028,16621.05.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) DEUTERATED DERIVATIVES OF 6,8-BIS(BENZYLSULFANYL)OCTANOIC ACID
(FR) DÉRIVÉS DEUTÉRÉS DE L'ACIDE 6,8-BIS (BENZYLSULFANYL) OCTANOÏQUE
Abstract
(EN) The invention provides new deuterated derivatives of 6,8-bis(benzylsulfanyl)octanoic acid, pharmaceutical compositions thereof, and methods for treating cancer with the new compositions.
(FR) L'invention concerne de nouveaux dérivés deutérés de l'acide 6,8-bis (benzylsulfanyl) octanoïque, des compositions pharmaceutiques de ceux-ci, et des méthodes de traitement du cancer avec ces nouvelles compositions.
Latest bibliographic data on file with the International Bureau