Processing

Please wait...

Settings

Settings

Goto Application

1. WO2021003451 - DEVICES, SYSTEMS, AND KITS FOR ELECTRO-MECHANICAL DELIVERY AND METHODS OF USE THEREOF

Publication Number WO/2021/003451
Publication Date 07.01.2021
International Application No. PCT/US2020/040784
International Filing Date 02.07.2020
IPC
B01J 19/08 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
08Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
C12M 1/42 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
42Apparatus for the treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic wave
C12N 13/00 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
13Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
Applicants
  • KYTOPEN CORPORATION [US]/[US]
Inventors
  • GARCIA, Paulo, Andres
  • MCCORMACK, Rameech
  • SIDO, Jessica
  • HEMPHILL, James
  • BRALOWER, Harrison
  • BEIGHLEY, Ross
  • BUIE, Cullen
  • GRANT, Bethany
Agents
  • BELLIVEAU, Michael, J.
Priority Data
62/869,95802.07.2019US
PCT/US2019/05837528.10.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) DEVICES, SYSTEMS, AND KITS FOR ELECTRO-MECHANICAL DELIVERY AND METHODS OF USE THEREOF
(FR) DISPOSITIFS, SYSTÈMES, ET KITS POUR UNE ADMINISTRATION ÉLECTRO-MÉCANIQUE ET PROCÉDÉS D'UTILISATION DE CES DERNIERS
Abstract
(EN)
Devices, systems, and kits for cell transfection are provided. A device includes a first electrode, a second electrode, and an electroporation zone therebetween where an electrical potential difference applied to the first and second electrodes generates an electric field in the electroporation zone sufficient to transfect at least a subset of the cells in the flow path. Methods of introducing a composition into at least a portion of a plurality of cells using the devices, systems, and kits of the invention are also provided.
(FR)
L'invention concerne des dispositifs, des systèmes, et des kits pour la transfection cellulaire. Un dispositif comprend une première électrode, une seconde électrode, et une zone d'électroporation entre celles-ci dans laquelle une différence de potentiels électriques appliquée aux première et seconde électrodes génère un champ électrique dans la zone d'électroporation suffisant pour transfecter au moins un sous-ensemble des cellules dans le chemin d'écoulement. L'invention concerne également des procédés d'introduction d'une composition dans au moins une partie d'une pluralité de cellules à l'aide des dispositifs, des systèmes et des kits selon l'invention.
Latest bibliographic data on file with the International Bureau