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1. WO2020242010 - PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ATOPIC DERMATITIS, CONTAINING FERMENTATION PRODUCT OF CARICA PAPAYA LINN.

Publication Number WO/2020/242010
Publication Date 03.12.2020
International Application No. PCT/KR2020/001739
International Filing Date 07.02.2020
IPC
A61K 36/185 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
A61P 17/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
A23L 33/105 2016.01
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
105Plant extracts, their artificial duplicates or their derivatives
A23L 29/00 2016.01
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
29Foods or foodstuffs containing additives; Preparation or treatment thereof
A61K 8/9789 2017.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
96containing materials, or derivatives thereof, of undetermined constitution
97from algae, fungi, lichens or plants; from derivatives thereof
9783Angiosperms
9789Magnoliopsida
A61Q 19/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19Preparations for care of the skin
Applicants
  • 서울대학교 산학협력단 SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION [KR]/[KR]
Inventors
  • 조명행 CHO, Myung Haing
  • 이아영 LEE, Ah Young
Agents
  • 김순웅 KIM, Soon Woong
Priority Data
10-2019-006266828.05.2019KR
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ATOPIC DERMATITIS, CONTAINING FERMENTATION PRODUCT OF CARICA PAPAYA LINN.
(FR) COMPOSITION PHARMACEUTIQUE POUR LA PRÉVENTION OU LE TRAITEMENT DE LA DERMATITE ATOPIQUE, CONTENANT UN PRODUIT DE FERMENTATION DE CARICA PAPAYA LINN.
(KO) 파파야 발효물을 포함하는 아토피 피부염의 예방 또는 치료용 약학적 조성물
Abstract
(EN)
The present invention relates to a pharmaceutical composition for preventing or treating atopic dermatitis, and a quasi-drug composition, a food composition or a cosmetic composition for preventing or alleviating atopic dermatitis, all of which contain a fermentation product of Carica papaya Linn. A fermentation product of Carica papaya Linn. according to the present invention, uses Carica papaya Linn., which is a natural product, and thus has few side effects and effectively reduces skin lesions and the number of mast cells, and significantly reduces the levels of intracytoplasmic NF-κB and IκBα, which are involved in the expression of inflammatory genes, and thus is expected to be effectively used in the development of pharmaceuticals, health functional foods, cosmetics and the like for the prevention, alleviation or treatment of atopic dermatitis.
(FR)
La présente invention concerne une composition pharmaceutique pour prévenir ou traiter la dermatite atopique, et une composition quasi-médicamenteuse, une composition alimentaire ou une composition cosmétique pour prévenir ou soulager la dermatite atopique, toutes ces compositions contenant un produit de fermentation de Carica papaya Linn. Un produit de fermentation de Carica papaya Linn., selon la présente invention, utilise Carica papaya Linn., qui est un produit naturel, et présente de ce fait peu d'effets indésirables et diminue efficacement les lésions cutanées et le nombre de mastocytes, et diminue significativement les niveaux de NF-κB et IκBα intracytoplasmiques, lesquels sont impliqués dans l'expression de gènes pro-inflammatoires, et il est donc attendu que ce produit de fermentation puisse être efficacement utilisé dans le développement de produits pharmaceutiques, d'aliments fonctionnels de santé, de cosmétiques et similaires pour la prévention, le soulagement ou le traitement de la dermatite atopique.
(KO)
본 발명은 파파야 발효물을 포함하는 아토피 피부염의 예방 또는 치료용 약학적 조성물, 아토피 피부염의 예방 또는 개선용 의약외품 조성물, 식품 조성물 또는 화장료 조성물에 관한 것이다. 본 발명에 따른 파파야 발효물은 천연물인 파파야를 이용하여 부작용이 거의 없을 뿐만 아니라, 피부 병변 및 비만 세포 수를 효과적으로 감소시키고, 염증 유발 유전자의 발현에 관여하는 세포질 내의 NF-κB 및 IκBα 수준을 유의하게 감소시켜, 아토피 피부염의 예방, 개선 또는 치료를 위한 의약품, 건강기능식품 및 화장품 등의 개발에 유용하게 이용될 수 있을 것으로 기대된다.
Also published as
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