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1. WO2020232439 - METHODS AND MATERIALS FOR TREATING CANCER

Publication Number WO/2020/232439
Publication Date 19.11.2020
International Application No. PCT/US2020/033413
International Filing Date 18.05.2020
IPC
A61K 31/4196 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
41961,2,4-Triazoles
A61P 29/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
A61P 31/12 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07D 403/12 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
403Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/167
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
Applicants
  • MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH [US]/[US]
Inventors
  • WITZIG, Thomas E.
  • WU, Xiaosheng
  • ABEYKOON, Jithma P.
Agents
  • WILLIS, Margaret S.
  • FINN III, J. Patrick
Priority Data
62/848,94816.05.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS AND MATERIALS FOR TREATING CANCER
(FR) MÉTHODES ET SUBSTANCES POUR LE TRAITEMENT DU CANCER
Abstract
(EN)
This document provides methods and materials involved in treating cancer. For example, this document provides methods and materials for using one or more inhibitors of a chromosomal maintenance 1 (CRM1) polypeptide in combination with one or more salicylates to treat cancer in a mammal (e.g., a human).
(FR)
La présente invention concerne des méthodes et des substances impliquées dans le traitement du cancer. Par exemple, ce document concerne des méthodes et des substances pour utiliser un ou plusieurs inhibiteurs d'un polypeptide de maintien chromosomique 1 (CRM1) en combinaison avec un ou plusieurs salicylates pour traiter le cancer chez un mammifère (par exemple, un être humain).
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