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1. WO2020230122 - PEPTIDES FOR THE TREATMENT OF CANCER

Publication Number WO/2020/230122
Publication Date 19.11.2020
International Application No. PCT/IL2020/050511
International Filing Date 12.05.2020
IPC
A61K 38/57 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
55Protease inhibitors
57from animals; from humans
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
CPC
A61K 38/57
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
55Protease inhibitors
57from animals; from humans
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
Applicants
  • YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. [IL]/[IL]
Inventors
  • WORMSER, Uri
Agents
  • BURSTEIN, Tal
  • WEBB, Cynthia
  • ARONIS, Zeev
  • FINAROV, Igal
  • GANOR, Sharon
  • HORNIK, Vered
  • NOY, Adi
  • POTASH, Shay
  • RAZ, Sefi
  • SCHICKLER, Hedva
  • SCHVARTZ, Iris
  • TRAVITSKY, Nina
  • WAINSCHTEIN, Silvy
  • WEBB, Yael
  • ZIPOR, Gadi
Priority Data
62/846,75713.05.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PEPTIDES FOR THE TREATMENT OF CANCER
(FR) PEPTIDES POUR LE TRAITEMENT DU CANCER
Abstract
(EN)
Compositions and methods for treating cancer are provided, using peptides derived from the C-terminus of protein C inhibitor (PCI) having anti-tumor activity. Further provided are novel peptide conjugates, comprising peptides derived from the C-terminus of PCI conjugated to a biotinyl moiety.
(FR)
L'invention concerne des compositions et des procédés de traitement du cancer, à l'aide de peptides dérivés de l'extrémité C-terminale de l'inhibiteur de protéine C (PCI) ayant une activité antitumorale. L'invention concerne en outre de nouveaux conjugués peptidiques, comprenant des peptides dérivés de l'extrémité C-terminale de PCI conjuguées à une fraction biotinyle.
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