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1. WO2020223704 - ANTI-GALECTIN-9 ANTIBODIES AND USES THEREOF

Publication Number WO/2020/223704
Publication Date 05.11.2020
International Application No. PCT/US2020/031184
International Filing Date 01.05.2020
IPC
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07K 16/28 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
G01N 33/574 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
Applicants
  • NEW YORK UNIVERSITY [US]/[US]
  • PURETECH HEALTH, LLC [US]/[US]
Inventors
  • KOIDE, Shohei
  • MILLER, George
  • KOIDE, Akiko
  • CHEN, Linxiao
  • FILIPOVIC, Aleksandra
  • ELENKO, Eric
  • BOLEN, Joseph
Agents
  • WATT, Rachel, S.
  • ROMAN, Paul, J.
  • DIMAIO, John, T. M.
  • LOPINSKI, John, D.
  • KADLE, Ranjana
Priority Data
62/841,73201.05.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ANTI-GALECTIN-9 ANTIBODIES AND USES THEREOF
(FR) ANTICORPS ANTI-GALECTINE-9 ET LEURS UTILISATIONS
Abstract
(EN)
Disclosed herein are methods for identifying a subject as having certain solid cancers such as breast cancer, colorectal colon cancer, or non-small cell lung cancer, or being at risk for the cancer based on the level of Galectin-9 in a biological sample (e.g., a blood sample) from a subject suspected of having the solid cancer.
(FR)
L'invention concerne des méthodes permettant d'identifier un sujet ayant certains cancers solides tels que le cancer du sein, le cancer colorectal, ou le cancer du poumon non à petites cellules, ou présentant un risque d'avoir un cancer sur la base du taux de galectine-9 dans un échantillon biologique (par exemple, un échantillon de sang) provenant d'un sujet suspecté d'avoir le cancer solide.
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