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1. WO2020223587 - CALCULATING CARDIAC OUTPUT OF A PATIENT UNDERGOING VENO-VENOUS EXTRACORPOREAL BLOOD OXYGENATION

Publication Number WO/2020/223587
Publication Date 05.11.2020
International Application No. PCT/US2020/030916
International Filing Date 01.05.2020
IPC
A61M 1/36 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
A61M 1/16 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
14Dialysis systems; Artificial kidneys; Blood oxygenators
16with membranes
A61B 5/029 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
02Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
026Measuring blood flow
029Measuring blood output from the heart, e.g. minute volume
A61B 5/1455 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
145Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
1455using optical sensors, e.g. spectral photometrical oximeters
A61B 5/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
A61B 5/0275 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
02Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
026Measuring blood flow
0275using tracers, e.g. dye dilution
CPC
A61M 1/1603
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
14Dialysis systems; Artificial kidneys; Blood oxygenators; ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for haemofiltration, pheris
16with membranes
1601Control or regulation
1603Regulation parameters
A61M 1/1698
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
14Dialysis systems; Artificial kidneys; Blood oxygenators; ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for haemofiltration, pheris
16with membranes
1698Blood oxygenators with or without heat-exchangers
A61M 2205/3334
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
2205General characteristics of the apparatus
33Controlling, regulating or measuring
3331Pressure; Flow
3334Measuring or controlling the flow rate
A61M 2205/50
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
2205General characteristics of the apparatus
50with microprocessors or computers
A61M 2230/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
2230Measuring parameters of the user
04Heartbeat characteristics, e.g. ECG, blood pressure modulation
A61M 2230/20
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
2230Measuring parameters of the user
20Blood composition characteristics
Applicants
  • TRANSONIC SYSTEMS, INC. [US]/[US]
Inventors
  • KRIVITSKI, Nikolai M.
  • GALYANOV, Gregory
Agents
  • SHAW, Brian B.
  • ANDERSON, Andrew J.
  • MENASCO, Timothy W.
Priority Data
62/842,19202.05.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) CALCULATING CARDIAC OUTPUT OF A PATIENT UNDERGOING VENO-VENOUS EXTRACORPOREAL BLOOD OXYGENATION
(FR) CALCUL DU DÉBIT CARDIAQUE D'UN PATIENT SOUS OXYGÉNATION SANGUINE EXTRACORPORELLE VEINO-VEINEUSE
Abstract
(EN)
A system for calculating cardiac output of a patient on an extracorporeal blood oxygenation circuit, such as veno-venous extracorporeal membrane oxygenation, includes determining (i) a first arterial carbon dioxide content or surrogate and (ii) a first carbon dioxide content or surrogate in the blood delivered to the patient after passing the oxygenator corresponding to the first removal rate of carbon dioxide from the blood; establishing a second removal rate of carbon dioxide from the blood in the oxygenator in the extracorporeal blood oxygenation circuit; determining (i) a second arterial carbon dioxide content or surrogate and (ii) a second carbon dioxide content or surrogate in the blood delivered to the patient after passing the oxygenator corresponding to the second removal rate of carbon dioxide from the blood; and calculating a cardiac output of the patient corresponding to a blood flow rate through the extracorporeal blood oxygenation circuit, the first arterial carbon dioxide content or surrogate, the first carbon dioxide content or surrogate in the blood delivered to the patient after passing the oxygenator corresponding to the first removal rate of carbon dioxide from the blood; the second arterial carbon dioxide content or surrogate and the second carbon dioxide content or surrogate in the blood delivered to the patient after passing the oxygenator corresponding to the second removal rate of carbon dioxide from the blood.
(FR)
L'invention concerne un système de calcul du débit cardiaque d'un patient placé sous circuit d'oxygénation sanguine extracorporelle, par exemple, une oxygénation par membrane extracorporelle veino-veineuse, qui consiste à déterminer (i) une première teneur en dioxyde de carbone artériel ou un substitut et (ii) une première teneur en dioxyde de carbone ou un substitut dans le sang acheminé au patient après le passage par l'oxygénateur correspondant à un premier taux d'élimination de dioxyde de carbone dans le sang ; établir un second taux d'élimination de dioxyde de carbone dans le sang contenu dans l'oxygénateur du circuit d'oxygénation sanguine extracorporelle ; déterminer (i) une seconde teneur en dioxyde de carbone artériel ou un substitut et (ii) une seconde teneur en dioxyde de carbone ou un substitut dans le sang acheminé au patient après le passage par l'oxygénateur correspondant à un second taux d'élimination de dioxyde de carbone dans le sang ; et calculer un débit cardiaque du patient correspondant à un débit sanguin dans le circuit d'oxygénation sanguine extracorporelle, la première teneur de dioxyde de carbone artériel ou un substitut, la première teneur en dioxyde de carbone ou un substitut dans le sang acheminé au patient après le passage par l'oxygénateur correspondant au premier taux d'élimination de dioxyde de carbone dans le sang ; la seconde teneur en dioxyde de carbone artériel ou un substitut et la seconde teneur en dioxyde de carbone ou un substitut dans le sang acheminé au patient après le passage par l'oxygénateur correspondant au second taux d'élimination de dioxyde de carbone dans le sang.
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