Processing

Please wait...

Settings

Settings

Goto Application

1. WO2020223236 - NOVEL AAV CAPSIDS AND COMPOSITIONS CONTAINING SAME

Publication Number WO/2020/223236
Publication Date 05.11.2020
International Application No. PCT/US2020/030281
International Filing Date 28.04.2020
IPC
A61K 35/761 2015.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
66Microorganisms or materials therefrom
76Viruses; Subviral particles; Bacteriophages
761Adenovirus
A61K 39/23 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
23Parvoviridae, e.g. feline panleukopenia virus
C07K 14/005 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
C07K 14/015 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
01DNA viruses
015Parvoviridae, e.g. feline panleukopenia virus, human parvovirus
C12N 7/00 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
7Viruses, e.g. bacteriophages; Compositions thereof; Preparation or purification thereof
C12N 15/35 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
31Genes encoding microbial proteins, e.g. enterotoxins
33Genes encoding viral proteins
34Proteins from DNA viruses
35Parvoviridae, e.g. feline panleukopenia virus, human parvovirus
Applicants
  • THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA [US]/[US]
Inventors
  • NAMBIAR, Kalyani
  • WILSON, James, M.
Agents
  • COFFEY, Francis, J.
  • KODROFF, Cathy, A.
  • SMITH, George, A.
  • SCHALLER, Colleen, M.
  • BAK, William
Priority Data
62/840,18429.04.2019US
62/913,31410.10.2019US
62/924,09521.10.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NOVEL AAV CAPSIDS AND COMPOSITIONS CONTAINING SAME
(FR) NOUVELLES CAPSIDES DE VAA ET COMPOSITIONS LES CONTENANT
Abstract
(EN)
Provided herein are novel AAV capsids and rAAV comprising the same. In one embodiment, vectors employing a novel AAV capsid show increased transduction of a selected target tissue as compared to a prior art AAV.
(FR)
L'invention concerne de nouvelles capsides de VAA et des virus adéno-associés de recombinaison (VAAr) les comprenant. Dans un mode de réalisation, les vecteurs utilisant la nouvelle capside de VAA présentent une transduction accrue d'un tissu cible sélectionné par rapport à état de la technique de VAA.
Latest bibliographic data on file with the International Bureau