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1. WO2020222349 - PHARMACEUTICAL COMPOSITION AND HEALTH FUNCTIONAL FOOD FOR PREVENTING OR TREATING PERIPHERAL NEURODEGENERATIVE DISEASES

Publication Number WO/2020/222349
Publication Date 05.11.2020
International Application No. PCT/KR2019/006214
International Filing Date 23.05.2019
IPC
A61K 35/30 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
30Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
A61K 31/7076 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7042Compounds having saccharide radicals and heterocyclic rings
7052having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706containing six-membered rings with nitrogen as a ring hetero atom
7064containing condensed or non-condensed pyrimidines
7076containing purines, e.g. adenosine, adenylic acid
A61P 25/28 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
28for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
A23L 33/10 2016.01
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
Applicants
  • 동아대학교 산학협력단 DONG-A UNIVERSITY RESEARCH FOUNDATION FOR INDUSTRY-ACADEMY COOPERATION [KR]/[KR]
Inventors
  • 손은정 SOHN, Eun Jung
  • 박환태 PARK, Hwan Tae
Agents
  • 두호특허법인 DOOHO IP LAW FIRM
Priority Data
10-2019-005013329.04.2019KR
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) PHARMACEUTICAL COMPOSITION AND HEALTH FUNCTIONAL FOOD FOR PREVENTING OR TREATING PERIPHERAL NEURODEGENERATIVE DISEASES
(FR) COMPOSITION PHARMACEUTIQUE ET ALIMENT DIÉTÉTIQUE FONCTIONNEL DE PRÉVENTION OU DE TRAITEMENT DE MALADIES NEURODÉGÉNÉRATIVES PÉRIPHÉRIQUES
(KO) 말초신경계 퇴행성 질환의 예방 또는 치료용 약학적 조성물 및 건강기능식품
Abstract
(EN)
The present invention relates to a pharmaceutical composition and a health functional food contain exosomes derived from Schwann cells treated with cyclic adenosine-3', 5'-monophosphate (cAMP), thereby inhibiting the proliferation of Schwann cells so as to enable the prevention or treatment of peripheral neurodegenerative diseases.
(FR)
La présente invention concerne une composition pharmaceutique et un aliment diététique fonctionnel contenant des exosomes dérivés de cellules de Schwann traitées avec de l'adénosine-3',5'-monophosphate cyclique (AMPc), ce qui permet d'inhiber la prolifération de cellules de Schwann de façon à permettre la prévention ou le traitement de maladies neurodégénératives périphériques.
(KO)
본 발명은 cAMP(사이클릭 아데노신-3', 5'-모노포스페이트) 처리한 슈반세포에서 유래된 엑소좀을 포함함으로써, 슈반세포 증식을 억제하여 말초신경계 퇴행성 질환을 예방 또는 치료할 수 있는 약학적 조성물 및 건강기능식품에 관한 것이다.
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