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1. WO2020222046 - A BIOSENSING DEVICE FOR SEPARATING BLOOD PLASMA AND TESTING THEREON

Publication Number WO/2020/222046
Publication Date 05.11.2020
International Application No. PCT/IB2020/050976
International Filing Date 07.02.2020
IPC
G01N 33/49 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
483Physical analysis of biological material
487of liquid biological material
49blood
A61B 5/145 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
145Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
Applicants
  • DIASYS DIAGNOSTICS INDIA PVT. LTD. [IN]/[IN]
Inventors
  • MATHUR, Vijaywanth
  • SAINI, Amardeep Singh
  • MAMDAPURKAR, Ramesh
  • SANE, Nikhil
Agents
  • KHURANA & KHURANA, ADVOCATES & IP ATTORNEYS
Priority Data
20192101727830.04.2019IN
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) A BIOSENSING DEVICE FOR SEPARATING BLOOD PLASMA AND TESTING THEREON
(FR) DISPOSITIF DE BIODÉTECTION POUR SÉPARER LE PLASMA SANGUIN ET LE TESTER
Abstract
(EN)
The present disclosure provides a biosensing device for testing blood plasma from a sample of undiluted blood. The device comprises a sample loading pad that is adapted to receive the blood sample. The sample loading pad is made of a material that is adapted to selectively absorb red blood corpuscles (RBCs), thereby separating the plasma component from the RBCs. The sample loading pad is coupled to a plasma suction membrane that is configured to extract the plasma component from the sample loading pad and transport it along its length. The plasma suction membrane is coupled to a sensor and the sensor has a formulation provided on it such that the formulation receives the plasma being transported. The formulation reacts with the plasma to generate an electrochemical signal that is particular to the formulation. Analysis of the electrochemical signal provides information of the plasma particular to the formulation used.
(FR)
La présente invention concerne un dispositif de biodétection pour tester le plasma sanguin à partir d'un échantillon de sang non dilué. Le dispositif comprend un tampon de chargement d'échantillon qui est conçu pour recevoir l'échantillon de sang. Le tampon de chargement d'échantillon est constitué d'un matériau qui est conçu pour absorber sélectivement les globules rouges (RBC), permettant ainsi la séparation du composant plasmatique des globules rouges. Le tampon de chargement d'échantillon est couplé à une membrane d'aspiration de plasma qui est conçue pour extraire le composant plasmatique du tampon de chargement d'échantillon et le transporter sur sa longueur. La membrane d'aspiration de plasma est couplée à un capteur et une formulation est fournie sur le capteur de telle sorte que la formulation reçoit le plasma transporté. La formulation réagit avec le plasma pour générer un signal électrochimique qui est spécifique de la formulation. L'analyse du signal électrochimique fournit des informations relative au plasma spécifique de la formulation utilisée.
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